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Development of the electricity stimulation drugs discharge chip, and its practical application to the discharge control that combined lbiosensor

Development of the electricity stimulation drugs discharge chip, and its practical application to the discharge control that combined lbiosensor
电刺激药物放电芯片的研制及其在结合生物传感器放电控制中的实际应用
批准号:
15590035
负责人:
KASHIWAGI Yoshitomo
金额:
$2.37万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2003
资助国家:
日本
项目状态:
已结题
起止时间:
2003 至 2004

项目摘要

项目成果

KASHIWAGI Yoshitomo的其他基金

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中文摘要
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英文摘要
This research did the research regarding the discharge control that combined the development and biosensor of the electricity stimulation drugs discharge chip. It was able to produce it by fixating the cation nature drugs on the foundation by utilizing the interaction of static electricity by surface castings after the element that can discharge the drugs by a direct reaction with the electrode covered Nafion on the foundation electrode. On the other hand, an indirect electricity reaction style element does production the pyrrole derivative that replaced the bipyridinium salt that turns on the discharge drugs pair ion and able to produce by fixating upward a foundation by an electrochemical polymerization reaction. By controlling the controlled potential electrolysis, even in either element that was produced these the discharge quantity of the drugs that is fixed able to be controlled release. On the other hand, the discharge quantity of the drugs that is fixed able to be controlled re … More lease, by controlling a/the setting potential in the controlled current electrolysis. Furthermore, by making a/the setting current minimum it came the discharge start of the drugs that is fixed with a delay.Next, I did the research regarding the unification between the electricity stimulation drugs discharge chip and biosensor. The insulin was discharged from the drugs discharge element when it reached the treatment area, as I tried the discharge control of the insulin that is diabetes treatment medicine while giving monitoring to the target when it combines, passes the drugs discharge element and glucose sensor first of all. Also, make the storeroom the pyramid state such that the drugs delivery utilize the technology of microinjection etc.to the foundation by using, silicon aiming at, the development of a possible element with the long time cycle and able to fill up little quantity precisely and cover the surface in the gold membrane where can prevent the corrosion by oxygen and chlorine ion etc.and overturned with silicon dioxy film to also prevent corrosion even positive pole and, the negative pole. The drugs fixate the functionability material that discharging by electricity stimulation on the positive pole of this element, the corrosiveness inside the living body was investigated. This electricity stimulation drugs discharge chip see the wisdom which the drugs delivery are possible with the long time cycle, without being corroded without receiving the influence at all during the solution of the component similar to living body inside as a result, and obtained. Less
期刊论文(26)
专著(0)
科研奖励(0)
会议论文
Yoshitomo Kashiwagi: "Oxidation of Alcohols with Nitroxyl Radical under Polymer-supported Two Phase Conditions"New Journal Chemistry. 27. 1545-1549 (2003)
Yoshitomo Kashiwagi:“聚合物支持的两相条件下硝基自由基对醇的氧化”新化学杂志。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
Organic Electrocatalysis
有机电催化
DOI: --
发表时间: 2005
期刊: Encyclopedia of Electrochemistry(eds.by Allen J.Bard and Martin Stratmann)(Wiley-VCH, Weinheim, Berlin) Vol.10(in press)
影响因子: --
作者: [M.Sakoh, T.Okazaki, Y.Nagaoka, K.Asami, Theodore Kuwana et al.]
通讯作者: Theodore Kuwana et al.
DOI: --
发表时间: 2004
期刊: Synlett 14
影响因子: --
作者: [H.Ohno, Y.Nagaoka, K.Tomioka, Akira Toyama, Yoshitomo Kashiwagi et al.]
通讯作者: Yoshitomo Kashiwagi et al.
Aihua Liu: "Polyelectrolyte Multilayer Films Containing Ferrocene : Effect of Polyelectrolyte Type and Ferrocene Contents in the Film on the Redox Properties"Electroanalysis. 15. 1139-1142 (2003)
刘爱华:“含二茂铁的聚电解质多层膜:膜中聚电解质类型和二茂铁含量对氧化还原性能的影响”电分析。
DOI: --
发表时间:
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影响因子: --
作者: []
通讯作者:
15
    Development of Skin Absorption Style Drugs Delivery Medical Device for Oder Maid Drug Medicine
    • 批准号:
      23590195
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.41万
    • 财政年份:
      2011
    • 负责人:
      KASHIWAGI Yoshitomo
    • 依托单位:
    Construction of Next Generation Type Drugs Delivery System and Development to Order-made Medicine
    • 批准号:
      20590155
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2008
    • 负责人:
      KASHIWAGI Yoshitomo
    • 依托单位: