On-site Analysis of the Endocrine-disrupting Alkylphenolic Compounds Based upon the Redox Recycling at the Applied Potential of 0 V

建立了环境水体中内分泌干扰性烷基酚类化合物的现场分析系统。该系统包括二茂铁衍生物的安培检测，使用烷基链涂层电极上的氧化还原循环，固相衍生化结合环境水的固相萃取，和微型分离.基于氧化还原循环的二茂铁基酚类衍生物的安培检测建立了一种基于二茂铁基酚的还原态和氧化态分别与亚铁氰化物和硝酸铁反应而连续再生的灵敏检测方法，用于内分泌干扰性烷基酚类化合物的HPLC分析。在放大氧化电流的情况下，检测限为10 μ <-12>mol/L水平。然而，在施加电势为0 V时，还原电流的放大率约为10.2。烷基酚的固相衍生化 ...更多信息 研究了内分泌干扰性烷基酚类化合物在C_ -改性硅胶（ODS）上的甲苯磺酰化和丹磺酰化反应<18>，以建立一种环境友好、高效的衍生化HPLC分析方法。固相水丹磺酰化系统已被纳入从自来水固相萃取进行的预浓缩步骤。即使是浓度小于10 μ <-11>mol/L的酚类物质，富集后也能有效地进行丹磺酰化，得到清晰的色谱图。固相衍生化也适用于其它体系，包括转化成磺酰基连接的可检测产物.干扰内分泌的烷基酚类化合物现场分析系统的建立本人提出了二茂铁衍生物的现场分析系统，该系统包括在烷基链涂层电极上的氧化还原循环安培检测、固相衍生化与环境水固相萃取相结合以及微量分离。少

The on-site analytical system for the endocrine-disrupting alkylphenolic compounds in environmental water has been proposed. The system consists of amperometric detection of the ferrocenoyl derivatives using the redox recycling on an alkyl chain-coated electrode, the solid-phase derivatization combined with the solid-phase extraction of environmental water, and the micro-scale separation.1. Amperometric Detection of the Ferrocenoyl Derivatives Based on the Redox RecyclingA sensitive detection method based upon continuous regeneration of the reduced and oxidized forms of the ferrocenoyl phenols by reaction with ferrocyanide and ferric nitrate is proposed for HPLC analyses of endocrine disruptive alkylphenolic compounds, respectively. In the case of the amplification of the oxidation current the detection limit is the 10^<-12> mol/L level. However, the amplification ratio for the reduction current at the applied potential of 0 V is about 10.2. Solid-phase Derivatization of the Alkylpheno … More lic CompoundsThe tosylation and dansylation reactions of the endocrine-disruptive alkylphenolic compounds on a C_<18>-modified silica gel (ODS) instead of organic solvents were investigated with the aim of developing an enviromnent-friendly and efficient derivatization method for the HPLC analyses. The solid-phase aqueous dansylation system has been incorporated into a preconcentration step performed by solid-phase extraction from tap water. Even the phenols at concentrations less than 10^<-11> mol/L can be efficiently dansylated after enrichment and give a clear chromatogram. The solid-phase derivatization is applicable to the other systems involving conversion into the detectable products inked by the sulfonyl group.3. Proposal of the On-site Analytical System for the Endocrine-Disrupting Alkylphenolic CompoundsI have proposed the on-site analytical system consisting of amperometric detection of the ferrocenoyl derivatives using the redox recycling on an alkyl chain-coated electrode, the solid-phase derivatization combined with the solid-phase extraction of environmental water, and the micro-scale separation. Less