Development of FRP composed by bioactive glass fiber and polymer for bone reconstruction

本研究的目的是开发一种由生物活性玻璃纤维和可生物降解聚合物组成的新型玻璃钢材料，用于骨重建。研究了Na_2O-CaO-TiO_2-SiO_2(NCTS)的抗拉强度和溶解度。NCTS玻璃纤维在纯水中浸泡24小时的拉伸强度约为浸泡前的49.2%。暴露在纯水中会迅速降低NCTS玻璃纤维的拉伸强度。纯水浸泡的样品在30分钟内表现出碱性。溶液的pH值在10左右，pH值不随时间变化。NCTS玻璃纤维在浸泡水中的含量随时间的延长而增加。浸泡30d后，水中Na2O、CaO、TiO2、SiO_2的质量分数分别为9.0、0、0、6.5%，在模拟体液中浸泡后，NCTS玻璃纤维的拉伸强度有所提高。NCTS玻璃纤维在模拟体液浸泡10天后，其拉伸强度为浸泡前的110%，纯水浸泡后的NCTS玻璃纤维表面形态不均匀，呈不规则形状。另一方面，NCTS玻璃纤维在模拟体液中浸泡后的扫描电子显微镜图像显示，NCTS玻璃纤维上有结晶的磷灰石。

The purpose of this research was to develop a new FRP material composed by bioactive glass fiber and biodegradable polymer for bone reconstruction. The tensile strength and solubility of Na_2O-CaO-TiO_2-SiO_2 (NCTS) have been studied. The tensile strength of NCTS glass fiber at 24 hours of the immersion of purity water was about 49.2 % of that before the immersion. The exposure to purely water rapidly decreased the tensile strength of the NCTS glass fiber. A purely water immersed specimens exhibit alkaline properties at 30 minutes. The pH of the solution was about 10. Its pH did not change with time. The contents of NCTS glass fiber dissolved in the immersed water, and these amounts increased with time. At 30 days after immersion, the amount of Na_2O, CaO, TiO_2, SiO_2 in water was 9.0, 0, 0, 6.5 mass%, respectively.In immersion of simulated body fluid, the tensile strength of NCTS glass fiber increased. NCTS glass fiber at 10 days after immersion of simulated body fluid showed the 110% tensile strength of NCTS glass fiber before immersion.The surface morphology of NCTS glass fiber after immersion of purely water was heterogeneous, showing irregular shape. On the other hand, SEM image of the NCTS glass fiber after immersion of the simulated body fluid show the crystalline apatites on the NCTS glass fiber.