The development and clinical application of osteoinductive bio-absorbable subperiosteum implant for orthodontic treatment.

正畸治疗骨诱导生物可吸收骨膜下种植体的研制及临床应用

基本信息

  • 批准号:
    15592182
  • 负责人:
  • 金额:
    $ 2.18万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 财政年份:
    2003
  • 资助国家:
    日本
  • 起止时间:
    2003 至 2006
  • 项目状态:
    已结题

项目摘要

In orthodontic treatment, the securing of an anchor is one of the most important factors that must be taken into consideration in terms of developing a treatment plan and proceeding with that treatment. The clinical usefulness of orthodontic implants has now been widely accepted because they are not dependent on the degree of patient cooperation. However, the invasion of soft tissue and bone cannot be avoided, and it is necessary for orthodontic implants to be removed after treatment. In addition, since implants have become smaller, problems have arisen, such as the breakage of implants inside bone. Therefore, we have chosen to focus on the use of a bioabsorbable material for use as orthodontic implants.Study 1 : The purpose of this study was to investigate the possibility of using bioabsorbable implants as orthodontic anchorage. All implants used in this study were made from poly-L-lactic acid (PLLA ; molecular weight : 200,000), a bioabsorbable bone-bonding material. The implants wer … More e placed in the mandibles of beagle dogs. After implantation, traction was immediately applied to the third premolars (P3s) using the implants as anchorage. After the completion of each study period (3 and 6months) following installation, a tensile test, histological examination, and molecular weight measurement were performed. Therefore the authors reported a utility as anchorage for orthodontic treatment of bioabsorbable material using a lower jaw of a dog. However, the initial intensity was 14.75kgf but the mean breaking strength of the 6 month-groups in which continuous orthodontic force was applied was 3.47 kgf while that of the 6 month-groups in which no continuous orthodontic force was applied was 1.98 kgf.Study 2 : The aim of this study was to investigate the influence of coating by sputtering on the surface of implant for an extreme control.The results obtained were as follows : 1.Tensile strength of absorbable implant material compared it in the control group which was not coated, and the rate of decline of a group coated by sputtering showed a significantly low value. 2.Molecular weight of absorbable implant material compared it in the control group which was not coated, and the molecular weight of a group coated by sputtering showed a significantly high value. As for the coating by sputtering to implant, the likelihood that was useful for an intensity control of bioabsorbable implant was suggested.In these studies, we conducted in vivo evaluations and examinations of whether or not it is possible to apply implants made of polylactic acid for use as anchorage for orthodontic treatment. Less
在正畸治疗中,固定锚是在制定治疗计划和进行该治疗时必须考虑的最重要因素之一。正畸种植体的临床实用性现已被广泛接受,因为它们不依赖于患者的合作程度。但是,软组织和骨的侵入是不可避免的,并且需要在治疗后取出正畸植入物。此外,由于植入物已经变得更小,因此出现了问题,例如植入物在骨内的断裂。因此,我们选择专注于使用生物可吸收材料作为正畸implants.Study 1:本研究的目的是调查使用生物可吸收植入物作为正畸支抗的可能性。本研究中使用的所有植入物均由聚-L-乳酸(PLLA ;分子量:200,000)制成,这是一种生物可吸收骨结合材料。植入物是 ...更多信息 放置在比格犬的下颌骨中。种植体植入后,立即牵引第三前磨牙(P3),使用种植体作为支抗。在安装后完成每个研究期(3个月和6个月)后,进行拉伸试验、组织学检查和分子量测量。因此,作者报告了一种使用狗下颌骨进行生物可吸收材料正畸治疗的锚定工具。然而,初始强度为14.75kgf,但施加持续正畸力的6个月组的平均断裂强度为3.47 kgf,而不施加持续正畸力的6个月组的平均断裂强度为1.98 kgf。本研究的目的是研究植入物表面溅射涂层的影响,以进行极端控制。获得的结果如下:1.可吸收植入材料的抗拉强度与未涂层的对照组相比,溅射涂层组的下降率明显较低。2.可吸收植入材料的分子量与未涂覆的对照组相比,溅射涂覆的一组的分子量显示出显著高的值。至于通过溅射到植入物的涂层,建议的可能性,是有用的生物可吸收的植入物的强度控制。在这些研究中,我们进行了体内评价和检查,是否有可能应用由聚乳酸制成的植入物作为正畸治疗的支抗。少

项目成果

期刊论文数量(17)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Development of a titanium mesh plate subperiosteal implant Applied as orthodontic absolute anchorage.
开发钛网板骨膜下种植体作为正畸绝对支抗。
歯科矯正用固定源として応用する生体吸収性インプラントの表面処理が物性に与える影響
表面处理对正畸固定源生物可吸收种植体物理性能的影响
  • DOI:
  • 发表时间:
    2007
  • 期刊:
  • 影响因子:
    0
  • 作者:
    青木 泰樹;八木橋 敬介;宮澤 健;小川 清隆;河合 達志;後藤 滋巳
  • 通讯作者:
    後藤 滋巳
The use of bioabsorbable implants as orthodontic anchorage in dogs
使用生物可吸收种植体作为狗的正畸支抗
  • DOI:
  • 发表时间:
    2005
  • 期刊:
  • 影响因子:
    0
  • 作者:
    T.Aoki;K.Ogawa;K.Miyazawa;T.Kawai;S.Goto
  • 通讯作者:
    S.Goto
歯周病を伴う叢生症例の成人矯正治療 -固定源としてスケルタルアンカレッジを応用した1治験例-
成人牙周病拥挤病例的正畸治疗-以骨支抗作为固定源的临床试验-
  • DOI:
  • 发表时间:
    2006
  • 期刊:
  • 影响因子:
    0
  • 作者:
    宮澤健;蛭川幸史;田渕雅子;小川清隆;金子道生;白水紀充;栗田賢一;後藤滋巳
  • 通讯作者:
    後藤滋巳
矯正用固定源として応用する生体吸収性インプラントの表面処理が物性に与える影響
表面处理对正畸固定源生物可吸收种植体物理性能的影响
  • DOI:
  • 发表时间:
    2007
  • 期刊:
  • 影响因子:
    0
  • 作者:
    青木泰樹;八木橋敬介;宮濁建;小川清隆;河合達志;後藤滋巳
  • 通讯作者:
    後藤滋巳
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GOTO Shigemi其他文献

GOTO Shigemi的其他文献

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{{ truncateString('GOTO Shigemi', 18)}}的其他基金

The exploitation of effective tooth movement by the specific osteoclast inhibitor and the system of prevention on periodontal disease.
特异性破骨细胞抑制剂有效牙齿移动的开发及牙周病预防体系。
  • 批准号:
    24593115
  • 财政年份:
    2012
  • 资助金额:
    $ 2.18万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The development of effective tooth movement using the specific osteoclast inhibitor and the system of prevention on periodontal disease.
使用特定破骨细胞抑制剂开发有效的牙齿移动和牙周病预防系统。
  • 批准号:
    21592618
  • 财政年份:
    2009
  • 资助金额:
    $ 2.18万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
A EXPERIMANTAL STUDY OF CHANGES IN SYNTHESIS OF MMPs AND TIMPs FOR BONE RESORPTION ON ORTHODONTIC TREATMENT
正畸治疗中骨吸收MMPs和TIMPs合成变化的实验研究
  • 批准号:
    09672129
  • 财政年份:
    1997
  • 资助金额:
    $ 2.18万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

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对提高阿拉斯加州安克雷奇小学生学校膳食消耗和身体活动水平的全区举措进行评估
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