Plasma-modified peptides/proteins for multi-target anticancer treatment

研制了蒸汽放电等离子体对N2、CO2和空气进气的处理。我们还开发了CO2， N2和空气等离子体的反应化学，以了解短寿命物种的产生。我们的0D和1D模型现在已经准备好了；我们专注于开发2D模型。由于两相流体流动的复杂性，两相二维模型的标准化需要很长时间。我们的二维模型非常接近气、液相的实验条件。OD和1D模型COMSOL模型有助于预测通过物理参数无法检测到的极短反应物质。我们还测量了气相和液相中的反应物质。此外，我们使用化学分析试剂盒和荧光光谱法进行液相分析，使用FT-IR进行气相分析，测量了反应物质的变化。通过对等离子体处理萝卜种子的分析，了解了等离子体处理对萝卜种子萌发指数和生长的影响。并对种子内NO3-的生成进行了新的分析。我们还使用FTIR检查了气相中CO和O3等反应产物的生产。并采用化学分析法检测了水体中NH4+、NO3-、NO2-和H2O2的浓度。随后，我们还利用荧光光谱检查了水中OH自由基的生成。采用光学发射光谱法测定了气相中OH、N2二正体系、NO、CO、α - h的含量。仿真结果与实验结果吻合较好

We developed steamer discharge plasma working on N2, CO2, and Air feed gas. We also developed reaction chemistry for CO2, N2, and Air plasma to understand the production of short-lived species. Our 0D and 1D models are ready nowadays; we are focused on developing 2D models. 2D models in two different phases took a very long time to standardize due to complications in fluid flow in two distinct phases. Our 2D model is very close to the experimental conditions of the gas and liquid phase. OD and 1D model COMSOL model were helpful in predicting the very short reactive species those were are not possible to detect through the physical parameters. like We also measured the reactive species in the gas and liquid phase. Further, we measured the changes in the reactive species using a chemical analysis Kit and Fluorescence spectroscopy for the liquid phase analysis, and FT-IR used for the gas phase analysis. We analyzed our plasma system on the radish seeds to find out the change in germination index and growth. Also new analyzed the production of the NO3- species inside the seeds. We also checked the production of reactive production in the gas phase like CO, and O3 using FTIR. And detected the NH4+, NO3-, NO2- and H2O2 concentrations in the water using chemical analysis. Later, we also checked the production of OH radical in the water using the Fluorescence spectroscopy. The detection of OH, N2 second positive system, NO, CO, Alpha-H were detected in the gas phase using Optical emission spectroscopy. Our Simulation results are in the good agreement with the experimental results