Plasma-modified peptides/proteins for multi-target anticancer treatment

我们开发了工作在氮气、二氧化碳和空气原料气上的蒸汽放电等离子体。我们还开发了二氧化碳、氮气和空气等离子体的反应化学，以了解短寿命物种的产生。我们的0D和1D模型现已准备就绪；我们专注于开发2D模型。由于两个不同阶段流体流动的复杂性，两个不同阶段的2D模型需要很长时间才能标准化。我们的二维模型与气相和液相的实验条件非常接近。OD模型和一维模型COMSOL模型有助于预测物理参数无法检测到的很短的活性物种。像我们一样，我们也测量了气相和液态中的反应物种。此外，我们还使用化学分析试剂盒和用于液相分析的荧光光谱以及用于气相分析的FT-IR来测量反应物种的变化。我们分析了我们的萝卜种子等离子体系统，以了解发芽指数和生长的变化。此外，还对种子内硝酸根的产生进行了新的分析。我们还使用FTIR检查了气相中反应性产物的产生，如CO和O3。并用化学分析法检测水中NH4+、NO3-、NO2-和H2O2的浓度。随后，我们还用荧光光谱检测了水中OH自由基的产生情况。用发射光谱检测了气相中的OH、N_2秒正离子体系、NO、CO、α-H。模拟结果与实验结果吻合较好

We developed steamer discharge plasma working on N2, CO2, and Air feed gas. We also developed reaction chemistry for CO2, N2, and Air plasma to understand the production of short-lived species. Our 0D and 1D models are ready nowadays; we are focused on developing 2D models. 2D models in two different phases took a very long time to standardize due to complications in fluid flow in two distinct phases. Our 2D model is very close to the experimental conditions of the gas and liquid phase. OD and 1D model COMSOL model were helpful in predicting the very short reactive species those were are not possible to detect through the physical parameters. like We also measured the reactive species in the gas and liquid phase. Further, we measured the changes in the reactive species using a chemical analysis Kit and Fluorescence spectroscopy for the liquid phase analysis, and FT-IR used for the gas phase analysis. We analyzed our plasma system on the radish seeds to find out the change in germination index and growth. Also new analyzed the production of the NO3- species inside the seeds. We also checked the production of reactive production in the gas phase like CO, and O3 using FTIR. And detected the NH4+, NO3-, NO2- and H2O2 concentrations in the water using chemical analysis. Later, we also checked the production of OH radical in the water using the Fluorescence spectroscopy. The detection of OH, N2 second positive system, NO, CO, Alpha-H were detected in the gas phase using Optical emission spectroscopy. Our Simulation results are in the good agreement with the experimental results