Spreading of SARS-CoV-2-laden aerosol particles in closed patient rooms

载有 SARS-CoV-2 的气溶胶颗粒在封闭的病房中传播

• 批准号: 468860716
• 负责人: Professor Dr.-Ing. Rüdiger Schwarze
• 金额: --
• 依托单位: Institut für Mechanik und Fluiddynamik
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2021
• 资助国家: 德国
• 起止时间: 2020-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/468860716?language=en
• 关键词: Spreading; SARS; CoV; laden; aerosol

The project investigates the airborne transport and spread of respiratory aerosol droplets loaded with SARS-CoV-2 viruses in closed patient rooms with and without high-volume air conditioning (HVAC) system. It is based on the hypothesis, that the structure of the air flow field in a patient room has a strong impact on the spread of aerosols and viruses. In detail, it will be examined, how the viral load in the aerosolized droplets correlates with the viral load in oral fluid samples from COVID-19 patients and how these correlations are influenced by the room climatic conditions, in particular the air flow field structure, humidity and the air exchange rate, the distance from and the behavior of the patients (breathing, speaking, singing, but not coughing or sneezing).Large-scale, long-term numerical simulations of the dispersed two-phase flow of aerosol droplets seeded with virus particles and the turbulent air flow in the patient room are performed. The aerosol droplets and virus particles are evaluated at selected monitoring points in the air flow field. Numerical data is compared with corresponding information from a patient study in order to identify important correlations for the airborne transport of virus particles.

该项目研究了在有和没有高容量空调（HVAC）系统的封闭病房中，载有SARS-CoV-2病毒的呼吸道气溶胶飞沫的空气传播和传播。它是基于这样的假设，即病房内的空气流场结构对气溶胶和病毒的传播有很大的影响。详细地，将检查雾化液滴中的病毒载量如何与来自COVID-19患者的口腔流体样本中的病毒载量相关，以及这些相关性如何受到室内气候条件的影响，特别是空气流场结构、湿度和空气交换率、与患者的距离和患者的行为（呼吸，说话，唱歌，但不咳嗽或打喷嚏）。大规模的，长期的数值模拟的分散两相流的气溶胶液滴接种病毒颗粒和湍流的空气流在病房中进行。在空气流场中的选定监测点处评估气溶胶液滴和病毒颗粒。数值数据进行了比较，从病人的研究，以确定重要的相关性的空气传播的病毒颗粒与相应的信息。