Cross sectional survey on risk factors for ischemic heart diseases in Japanese middle-aged female

日本中年女性缺血性心脏病危险因素横断面调查

• 批准号: 14570351
• 负责人: ONODA Toshiyuki
• 金额: $ 2.5万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14570351/
• 关键词: cohort study; microalbuminuria; C-reactive protein; BNP; physical checkup; medical checkup; CHD registry; stroke registry; 虚血性心疾患; 頚動脈エコー

To evaluate the relationship among C-reactive protein (CRP) levels, microalbuminuria, B-type Na+ Peptide (BNP) and other risk factors of cardio vascular disease (CVD), Iwate-KENCO study ( Iwate-KENpoku COhort study ) started in 2002. All subjects studied were recruited from NINOHE, MJYAKO and KUJI areas in Iwate prefecture. In 2002 -2003, 12, 144 participants were enrolled and blood pressure, total, LDL and HDL cholesterol levels, body mass index (BMJ), medical history, smoking arid drinking habits, CRP levels, urinary albumin excretion (UAE) levels and BNP levels were examined. In this study, 5,514 female aged 40-69 ( 58.0 +-7.9 ) were selected and the relationship among risk factors of CVD was investigated.The significant relationship between UAE levels and blood pressure, UAE and BMJ, UAE and CRP levels, CRP and blood pressure, CRP and BMJ, CRP and HbAlc, CRP and lipid were observed. The relationship between BNP levels and UAE, BNP and CRP levels were not significant.

为了评估C反应蛋白(CRP)水平、微量白蛋白尿、B型钠肽(BNP)与心血管疾病(CVD)的其他危险因素之间的关系，岩手健二研究(Iwate-Kenpoku队列研究)始于2002年。所有研究对象都来自岩手县尼诺河、MJYAKO和Kuji地区。2002年至2003年，12,144名受试者参加了血压、总胆固醇、低密度脂蛋白和高密度脂蛋白水平、体重指数(BMJ)、病史、吸烟和饮酒习惯、C反应蛋白(CRP)水平、尿白蛋白排泄(UAE)和BNP水平的检测。本研究以5514名40~69岁(58.0±7.9)岁的女性为研究对象，对其与心血管疾病危险因素之间的关系进行了研究，发现UAE水平与血压、UAE与BMJ、UAE与CRP、CRP与血压、CRP与BMJ、CRP与HbAlc、CRP与血脂之间存在显著的相关性。BNP水平与UAE、BNP、CRP水平无明显相关性。

项目成果

Toshiyuki Onoda, et al.: "Body mass index, blood pressure, serum lipids, HbAlc, smoking and drinking habits in inhabitants of Iwate prefecture"Iwate Jn of Public Health. 16-1. 82-89 (2004)

Toshiyuki Onoda等人：“岩手县居民的体重指数、血压、血脂、HbAlc、吸烟和饮酒习惯”岩手公共卫生杂志。

小野田敏行, 西信雄, 他5名: "岩手県北地域住民の性別年齢階級別BMI、血圧、血清脂質、HbA1c値、喫煙および飲酒状況について"岩手公衆衛生学会誌. 16・1. 82-89 (2004)

Toshiyuki Onoda、Nobuo Nishi 等 5 人：“岩手县北部地区居民按性别和年龄组划分的 BMI、血压、血脂、HbA1c 水平、吸烟和饮酒状况”岩手公共卫生学会杂志。 16・1。82-89（2004）