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Relationship between the morphological characteristics and the transmucosal gas exchange function in human middle ear cavity

人中耳腔形态特征与跨粘膜气体交换功能的关系

基本信息

批准号：
14571609
负责人：
YAMAMOTO Yutaka
金额：
$ 0.83万
依托单位：
NIIGATA UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2002
资助国家：
日本
起止时间：
2002 至 2003
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14571609/
关键词：
middle ear cavity transmucosal gas exchange nitrous oxide CT scan gas exchange surface area volume 経粘膜換 CTスキャ

项目摘要

There are few reports to evaluate the relationship between the function and morphological characteristic of middle ear cavity. In this research, the relationship between the transmucosal gas exchange function and the surface area and volume of middle ear cavity was investigated.1.Study to evaluate the relationship between surface area and volume in normal middle ear cavityMaterials were temporal bone CT scans of 23 patients with acoustic tumor without a past history of otitis media. The image data of CT scans were transported to a personal computer as DICOM formatted data, and analyzed by image analysis software. The perimeter and area of each air cell were measured, and then the surface area and volume of mastoid air cell system were calculated. The strong linear con-elation between the area and volume was confirmed.2.Study to evaluate the relationship between the morphological characteristics and the transmucosal gas exchange function in human middle ear cavityMaterials were 10 patients who undergo myringoplasty with dry tympanic membrane perforations without active inflammation in the middle ear cavity. At the time of operation under general anesthesia with the inhalation of nitrous oxide, increasing middle ear pressure caused by the diffusion of nitrous oxide was measured, and the gas exchange function was quantitatively evaluated. Surface area and volume of middle ear cavity were measured by CT scans. The strong correlations between the gas exchange ability and surface area, and the surface area and volume were confirmed.Human middle ear cavity had a large surface area corresponding to its large volume by having air cell systems, and the gas exchange function through the middle ear mucosa depended on the surface area. The morphological characteristic of middle ear cavity is of great advantage to regulating middle pressure by transmucosal gas exchange function.

评价中耳腔功能与形态特征之间关系的报道较少。本研究旨在探讨中耳黏膜气体交换功能与中耳腔表面积和体积的关系。1.探讨正常中耳腔表面积和体积的关系。材料来自23例无中耳炎病史的听神经瘤患者的颞骨CT扫描。CT扫描的图像数据以DICOM格式传输到个人计算机，并通过图像分析软件进行分析。测量各气室的周长和面积，计算乳突气室系统的表面积和体积。2.评价人中耳腔形态特征与经粘膜气体交换功能的关系材料：10例干性鼓膜穿孔，中耳腔内无活动性炎症的鼓膜修补术。在吸入一氧化二氮的全麻下手术时，测量一氧化二氮扩散引起的中耳压力升高，并定量评价气体交换功能。CT扫描测量中耳腔的表面积和体积。中耳腔的气体交换能力与表面积、表面积和体积有很强的相关性，人的中耳腔具有与其大体积相对应的较大表面积，通过中耳粘膜的气体交换功能依赖于表面积。中耳腔的形态特征有利于通过粘膜气体交换功能调节中压。