Study for mechanism of cell cycle regulation by ubiquitin ligase in triple-negative breast cancer
Study for mechanism of cell cycle regulation by ubiquitin ligase in triple-negative breast cancer
批准号:
21591671
负责人:
YAMAMOTO Yutaka
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
We studied clinical significance of ubiquitin ligase(skp2 and Fbw7) in breast cancer and potential of ubiquitin ligase targeting-therapy for breast cancer. Fbw7 downregulation and skp2 overexpression were significantly correlated with aggressive phenotype in breast cancer. Fbw7 knockdown led to suppression of proliferation in breast cancer cells.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1111/j.1349-7006.2010.01801.x
发表时间:
2011-02-01
期刊:
CANCER SCIENCE
影响因子:
5.7
作者:
[Ibusuki, Mutsuko, Yamamoto, Yutaka, Iwase, Hirotaka]
通讯作者:
Iwase, Hirotaka
DOI:
10.1007/s12282-009-0150-8
发表时间:
2009-10-01
期刊:
BREAST CANCER
影响因子:
4
作者:
[Yamamoto, Yutaka, Ibusuki, Mutsuko, Iwase, Hirotaka]
通讯作者:
Iwase, Hirotaka
System Theory for Mon-stationary Signals via Sampled-Data Control Theory and Its Applications
-
批准号:24360163
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.9万
-
财政年份:2012
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负责人:YAMAMOTO Yutaka
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依托单位:
Study of numerical analysis via control theory
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批准号:22656095
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2010
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负责人:YAMAMOTO Yutaka
-
依托单位:
Hybrid Signal Processing via Sampled-data Control Theory
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批准号:21360203
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.48万
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财政年份:2009
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负责人:YAMAMOTO Yutaka
-
依托单位:
New methodology in signal processing via sampled-data control theory and its development in new non-stationary system theory
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批准号:18360203
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.06万
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财政年份:2006
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负责人:YAMAMOTO Yutaka
-
依托单位:
General Theory of Digital Signal Processing via-Sampled Data Control Theory and Its Applications
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批准号:15360224
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.58万
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财政年份:2003
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负责人:YAMAMOTO Yutaka
-
依托单位:
Relationship between the morphological characteristics and the transmucosal gas exchange function in human middle ear cavity
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批准号:14571609
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.83万
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财政年份:2002
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负责人:YAMAMOTO Yutaka
-
依托单位:
Digital Signal Processing with Optimal Analog Performance via Sampled-data Control Theory
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批准号:12450172
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.45万
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财政年份:2000
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负责人:YAMAMOTO Yutaka
-
依托单位:
Sampled-Data Control & Digital Signal Processing
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批准号:08455196
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.22万
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财政年份:1996
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负责人:YAMAMOTO Yutaka
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依托单位:
New Theory for Sampled-Data Control Systems and Its Applications
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批准号:05452220
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.22万
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财政年份:1993
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负责人:YAMAMOTO Yutaka
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依托单位:
Fundamental Research on Learning and Intelligence in System Control
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批准号:02452180
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.26万
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财政年份:1990
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负责人:YAMAMOTO Yutaka
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依托单位:
Research in Method for Software Integration with Psychological Laboratory Network
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批准号:60810003
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$2.5万
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财政年份:1985
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负责人:YAMAMOTO Yutaka
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依托单位:
海外基金