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Study for mechanism of cell cycle regulation by ubiquitin ligase in triple-negative breast cancer

Study for mechanism of cell cycle regulation by ubiquitin ligase in triple-negative breast cancer
泛素连接酶调控三阴性乳腺癌细胞周期的机制研究
批准号:
21591671
负责人:
YAMAMOTO Yutaka
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
We studied clinical significance of ubiquitin ligase(skp2 and Fbw7) in breast cancer and potential of ubiquitin ligase targeting-therapy for breast cancer. Fbw7 downregulation and skp2 overexpression were significantly correlated with aggressive phenotype in breast cancer. Fbw7 knockdown led to suppression of proliferation in breast cancer cells.
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DOI: 10.1111/j.1349-7006.2010.01801.x
发表时间: 2011-02-01
期刊: CANCER SCIENCE
影响因子: 5.7
作者: [Ibusuki, Mutsuko, Yamamoto, Yutaka, Iwase, Hirotaka]
通讯作者: Iwase, Hirotaka
DOI: 10.1007/s12282-009-0150-8
发表时间: 2009-10-01
期刊: BREAST CANCER
影响因子: 4
作者: [Yamamoto, Yutaka, Ibusuki, Mutsuko, Iwase, Hirotaka]
通讯作者: Iwase, Hirotaka
System Theory for Mon-stationary Signals via Sampled-Data Control Theory and Its Applications
  • 批准号:
    24360163
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.9万
  • 财政年份:
    2012
  • 负责人:
    YAMAMOTO Yutaka
  • 依托单位:
Study of numerical analysis via control theory
  • 批准号:
    22656095
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.33万
  • 财政年份:
    2010
  • 负责人:
    YAMAMOTO Yutaka
  • 依托单位:
Hybrid Signal Processing via Sampled-data Control Theory
  • 批准号:
    21360203
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.48万
  • 财政年份:
    2009
  • 负责人:
    YAMAMOTO Yutaka
  • 依托单位:
New methodology in signal processing via sampled-data control theory and its development in new non-stationary system theory
  • 批准号:
    18360203
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.06万
  • 财政年份:
    2006
  • 负责人:
    YAMAMOTO Yutaka
  • 依托单位:
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