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Evaluation of vital tooth breaching with hydrogen peroxide more than 3O%

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基本信息

批准号：
14571862
负责人：
KAWADA Eiji
金额：
$ 1.79万
依托单位：
TOKYO DENTAL COLLEGE
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2002
资助国家：
日本
起止时间：
2002 至 2003
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14571862/
关键词：
Vital tooth Breaching Hydrogen peroxide Super oxide Hydroxyl radical metal ion Dentin VABSTRACT 歯牙漂白過酸化尿素エナメル質過酸化水素計歯髄

项目摘要

This research was to clarify the effects of peroxide on teeth after the tooth-whitener-application. An artificial root canal was prepared using the crown of human incisors filled with phosphate buffer solution. Tooth-whitener containing 30% hydrogen peroxide or 35% carbamide peroxide was applied according to the instructions with or without acid-etching pretreatment. Luminol-chemi luminescence was used to measure the quantity of peroxide that penetrated into the buffer within the root canal. The penetrated peroxide quantity ranged from 7 μ M to 100.5 μ M. The penetration quantity for the hydrogen peroxide-applied group was about 1.6-fold greater than that for the carbamide-applied group. The penetration quantity for the acid-etching pretreatment group exceeded about 4-fold greater than that of the non-pretreatment group. The whitener containing hydrogen peroxide consists of liquid and powder. Qualitative analysis of powder component of the whitener with EPMA showed that it contained Fe and Cu ions. This finding suggests that whitener affects on the tooth by means of hydrogen peroxide itself or the oxygen radical that generated with Fe or Cu ion. Hence, these findings suggest that the penetration of peroxide from whitener applied to the tooth surface might cause some discomfort after whitening treatment.

本研究旨在阐明过氧化氢在牙齿美白后对牙齿的影响。采用人门牙冠填充磷酸盐缓冲液制备人工根管。按说明书使用含30%过氧化氢或35%过氧化脲的牙齿增白剂，有或没有酸蚀预处理。用鲁米诺化学发光法测量过氧化物渗透到根管内缓冲液中的量。过氧化氢溶液的渗透量为7 ~ 100.5 μ M，过氧化氢溶液的渗透量是尿素溶液的1.6倍。酸蚀预处理组的侵彻量超过未预处理组的4倍左右。含双氧水的增白剂由液体和粉末组成。用EPMA对该增白剂粉末成分进行定性分析，发现其含有铁和铜离子。这一发现表明，增白剂对牙齿的影响是通过过氧化氢本身或由铁或铜离子产生的氧自由基。因此，这些研究结果表明，牙齿表面使用的增白剂对过氧化氢的渗透可能会在美白治疗后引起一些不适。