Carbonyl diisocyanate – a treasure trove for modern heavy main-group molecular chemistry

羰基二异氰酸酯——现代重主族分子化学的宝库

• 批准号: 470154745
• 负责人: Dr. Frank Tambornino
• 金额: --
• 依托单位: Institut für Allgemeine, Anorganische und Theoretische Chemie
• 依托单位国家: 德国
• 项目类别: Independent Junior Research Groups
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/470154745?language=en
• 关键词: Carbonyl; diisocyanate; treasure; trove; modern

Exploring the reactivity and properties of small molecules and ions is key to expanding our knowledge and discovering new areas of research and applications. Within the first sub-project we will focus on carbonyl diisocyanates with the general composition CCh(NCCh)2 (Ch = O – Se). The chemistry of carbonyl diisocyanate and diisothiocyanate is only scarcely explored despite offering a plethora of interesting possibilities for follow up chemistry. Additionally, their heavier congeners are unknown. Based on their differing reactivity we will explore the resulting carbamate and thiadiazine chemistry, the latter showing similarity towards nucleobases. Their coordination chemistry will also be focussed on. Heavy fulminates will be target of the second sub-project. The fundamental cyanate to fulminate transformation has recently been observed for 1-phosphaethynolate and its sulphur congener, prompting us to aim for syntheses of the arsenic/selenium congeners, too. Freeing of the heavy fulminates into their “free” quasibinary forms will then enable us to elucidate their chemistry in depth. Another structural motif in carbonyl diisocyanate is the carbonyl bond and we will focus on its heavy chalcogen congeners. Towards the syntheses of CCh(NCCh)2 there is the need for synthons with bespoke reactivity which we will focus on here.

探索小分子和离子的反应性和性质是扩大我们的知识和发现新的研究和应用领域的关键。在第一个子项目中，我们将重点关注一般组成为CCh（NCCh）2（Ch = O-Se）的羰基二异氰酸酯。羰基二异氰酸酯和二异硫氰酸酯的化学几乎没有探索，尽管为后续化学提供了大量有趣的可能性。此外，其较重的同系物也是未知的。基于它们不同的反应性，我们将探索所得的氨基甲酸酯和噻二嗪化学，后者显示出对核碱基的相似性。重雷酸盐将是第二个分项目的目标。最近观察到1-磷炔酸盐及其硫同系物的基本氰酸盐到雷酸盐的转化，促使我们也致力于砷/硒同系物的合成。将重雷酸盐释放成它们的“自由”准二元形式将使我们能够深入地阐明它们的化学性质。羰基二异氰酸酯中的另一个结构基序是羰基键，我们将重点关注其重硫族元素同系物。为了合成CCh（NCCh）2，需要具有定制反应性的质子，我们将在这里重点讨论。