Evaluation of Protective Clothing to Prevent Diisocyanate Exposures in the Collis

描述（由申请人提供）：普吉湾的碰撞维修行业由许多健康和安全做法无效的小企业组成。油漆喷涂和混合油漆过程除了具有吸入危险外，还在很大程度上导致油漆工的皮肤接触。异氰酸酯以高浓度存在于最终的“透明”涂层中。在华盛顿州，异氰酸酯是已知的刺激物、致敏物和与工作有关的哮喘的主要原因。画家使用防晒霜，但不一定要戴手套和穿工作服来保护皮肤。目前关于喷漆工防护服的有效性的资料很少，因为还没有对异氰酸酯的使用进行过系统的调查。目前可用的信息主要集中在舒适性，弹性，无绒质量或耐溶剂性，而不是耐异氰酸酯性。制造商和供应商关于异氰酸酯防护的兼容性图表有限且相互矛盾。这并不奇怪，因为异氰酸酯的化学特性使得难以用用于防护服的标准方法进行测试。我们提出了一个新的和系统的实验室和工作场所评估的有效性手套和工作服，以防止异氰酸酯。我们认识到，有许多变量会影响工人有效使用防护设备。因此，我们还将促进与画家的焦点小组分享我们的研究结果，并评估实施未来干预措施的战略。我们还将开发一种改进的分析方法，用于检测透明涂层中多异氰酸酯的复杂混合物。 公共卫生相关性：汽车碰撞维修行业使用的异氰酸酯被认为是一种职业性哮喘，这些工人患上与工作有关的哮喘的风险很高。该行业使用的防护服缺乏关于功效的基本数据。这项研究将评估防护服的有效性，如手套，防止汽车碰撞维修工人中的异氰酸酯暴露。我们还将开发一种改进的分析方法，用于检测透明涂层中多异氰酸酯的复杂混合物。

DESCRIPTION (provided by applicant): The collision repair industry in the Puget Sound is composed of numerous small businesses with ineffective health and safety practices. Paint spraying and mixing painting process, besides being an inhalation hazard, contribute largely to a painter's dermal exposure. Isocyanates are present in high concentration in the final "clear" coat. Isocyanates are known irritants, sensitizers, and a leading cause of work-related asthma in Washington State. Painters use respirators, but not necessarily gloves and coveralls to protect their skin. Little information currently is available on the effectiveness of protective clothing for spray painters because no systematic investigation for use with isocyanates has ever been conducted. The currently available information is largely focused on comfort, elasticity, lint-free qualities, or solvent resistance, rather than resistance to isocyanates. Manufacturer and supplier compatibility charts regarding protection from isocyanates is limited and conflicting. This is not surprising since isocyanates have chemical characteristics that make testing difficult with standard methods used for protective clothing. We are proposing a novel and systematic laboratory and workplace assessment of the efficacy of gloves and coveralls for protection against isocyanates. We recognize there are many variables affecting a worker's effective use of protective equipment. Therefore, we will also facilitate focus groups with painters to share our findings and assess strategies to implement future interventions. We will also develop an improved analytical method for detecting the complex mixtures of polyisocyanates in clear coats. Public Health Relevance: Isocyanates used in the auto-collision repair industry are recognized as an occupational asthma and these workers are at high risk for work-related asthma. protective clothing used in this industry lacks basic data on efficacy. This study will evaluate the effectiveness of protective clothing, such as gloves preventing isocyanate exposures among auto-collision repair workers. We will also develop an improved analytical method for detecting the complex mixtures of polyisocyanates in clear coats.