Evaluation of Protective Clothing to Prevent Diisocyanate Exposures in the Collis

描述（由申请人提供）：普吉特海湾的碰撞修理行业由许多小企业组成，这些小企业的健康和安全措施无效。喷漆和混合喷漆的过程，除了是一个吸入的危险，很大程度上有助于画家的皮肤暴露。异氰酸酯在最终的“透明”涂层中以高浓度存在。异氰酸酯是已知的刺激物、致敏剂，也是华盛顿州工作相关哮喘的主要原因。油漆工使用呼吸器，但不一定使用手套和工作服来保护皮肤。由于从未对使用异氰酸酯进行过系统的调查，目前关于喷涂工人防护服的有效性的信息很少。目前可获得的信息主要集中在舒适性、弹性、无绒性或耐溶剂性，而不是抗异氰酸酯。制造商和供应商关于防止异氰酸酯的兼容性图表是有限的和相互冲突的。这并不奇怪，因为异氰酸酯的化学特性使得使用防护服的标准方法进行测试变得困难。我们建议对手套和工作服防护异氰酸酯的功效进行新颖和系统的实验室和工作场所评估。我们认识到，影响工人有效使用防护装备的因素有很多。因此，我们还将促进与画家的焦点小组分享我们的发现，并评估实施未来干预措施的策略。我们还将开发一种改进的分析方法，用于检测透明涂层中复杂的多异氰酸酯混合物。

DESCRIPTION (provided by applicant): The collision repair industry in the Puget Sound is composed of numerous small businesses with ineffective health and safety practices. Paint spraying and mixing painting process, besides being an inhalation hazard, contribute largely to a painter's dermal exposure. Isocyanates are present in high concentration in the final "clear" coat. Isocyanates are known irritants, sensitizers, and a leading cause of work-related asthma in Washington State. Painters use respirators, but not necessarily gloves and coveralls to protect their skin. Little information currently is available on the effectiveness of protective clothing for spray painters because no systematic investigation for use with isocyanates has ever been conducted. The currently available information is largely focused on comfort, elasticity, lint-free qualities, or solvent resistance, rather than resistance to isocyanates. Manufacturer and supplier compatibility charts regarding protection from isocyanates is limited and conflicting. This is not surprising since isocyanates have chemical characteristics that make testing difficult with standard methods used for protective clothing. We are proposing a novel and systematic laboratory and workplace assessment of the efficacy of gloves and coveralls for protection against isocyanates. We recognize there are many variables affecting a worker's effective use of protective equipment. Therefore, we will also facilitate focus groups with painters to share our findings and assess strategies to implement future interventions. We will also develop an improved analytical method for detecting the complex mixtures of polyisocyanates in clear coats. Public Health Relevance: Isocyanates used in the auto-collision repair industry are recognized as an occupational asthma and these workers are at high risk for work-related asthma. protective clothing used in this industry lacks basic data on efficacy. This study will evaluate the effectiveness of protective clothing, such as gloves preventing isocyanate exposures among auto-collision repair workers. We will also develop an improved analytical method for detecting the complex mixtures of polyisocyanates in clear coats.