Evaluation of Protective Clothing to Prevent Diisocyanate Exposures in the Collis

描述(由申请人提供)：普吉特湾的碰撞修复行业由许多健康和安全做法无效的小企业组成。喷漆和混合喷漆过程，除了会造成吸入危险外，还很大程度上会导致画家的皮肤暴露。异氰酸酯在最终的“透明”涂层中浓度很高。异氰酸酯是已知的刺激物、致敏剂，也是华盛顿州职业性哮喘的主要原因。画家使用呼吸器，但不一定使用手套和工作服来保护他们的皮肤。目前关于喷漆工防护服有效性的信息很少，因为从未进行过与异氰酸酯一起使用的系统调查。目前可用的信息主要集中在舒适性、弹性、无绒毛质量或耐溶剂性上，而不是对异氰酸酯的耐受性。制造商和供应商关于异氰酸酯保护的兼容性图表是有限的和相互冲突的。这并不令人惊讶，因为异氰酸酯的化学特性使用于防护服的标准方法难以检测。我们建议在实验室和工作场所对手套和工作服对异氰酸酯的保护效果进行新颖和系统的评估。我们认识到，影响工人有效使用防护装备的变数很多。因此，我们还将促进有画家的焦点小组分享我们的研究结果，并评估实施未来干预措施的策略。我们还将开发一种改进的分析方法，用于检测透明涂层中复杂的多异氰酸酯混合物。 公共卫生相关性：汽车碰撞修理行业使用的异氰酸酯被认为是职业性哮喘，这些工人患职业性哮喘的风险很高。该行业使用的防护服缺乏有关功效的基本数据。这项研究将评估防护服的有效性，如手套，以防止汽车碰撞维修工人暴露于异氰酸酯。我们还将开发一种改进的分析方法，用于检测透明涂层中复杂的多异氰酸酯混合物。

DESCRIPTION (provided by applicant): The collision repair industry in the Puget Sound is composed of numerous small businesses with ineffective health and safety practices. Paint spraying and mixing painting process, besides being an inhalation hazard, contribute largely to a painter's dermal exposure. Isocyanates are present in high concentration in the final "clear" coat. Isocyanates are known irritants, sensitizers, and a leading cause of work-related asthma in Washington State. Painters use respirators, but not necessarily gloves and coveralls to protect their skin. Little information currently is available on the effectiveness of protective clothing for spray painters because no systematic investigation for use with isocyanates has ever been conducted. The currently available information is largely focused on comfort, elasticity, lint-free qualities, or solvent resistance, rather than resistance to isocyanates. Manufacturer and supplier compatibility charts regarding protection from isocyanates is limited and conflicting. This is not surprising since isocyanates have chemical characteristics that make testing difficult with standard methods used for protective clothing. We are proposing a novel and systematic laboratory and workplace assessment of the efficacy of gloves and coveralls for protection against isocyanates. We recognize there are many variables affecting a worker's effective use of protective equipment. Therefore, we will also facilitate focus groups with painters to share our findings and assess strategies to implement future interventions. We will also develop an improved analytical method for detecting the complex mixtures of polyisocyanates in clear coats. Public Health Relevance: Isocyanates used in the auto-collision repair industry are recognized as an occupational asthma and these workers are at high risk for work-related asthma. protective clothing used in this industry lacks basic data on efficacy. This study will evaluate the effectiveness of protective clothing, such as gloves preventing isocyanate exposures among auto-collision repair workers. We will also develop an improved analytical method for detecting the complex mixtures of polyisocyanates in clear coats.