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Functional Development of Neural Circuits

Functional Development of Neural Circuits
神经回路的功能发育
批准号:
07279102
负责人:
TSUMOTO Tadaharu
金额:
$57.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1998

项目摘要

项目成果

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中文摘要
翻译
该项目解决了神经回路如何形成和功能发展的问题,以便执行更高的大脑功能。为了阐明大脑神经回路形成和功能发育的机制,我们在这个项目中采取了多学科的方法。因此,具有不同方法的研究人员之间的密切合作对于该项目的成功至关重要。经过本研究项目成员之间的合作,我们成功地获得了许多优秀的成果,并在国际顶级期刊上发表。在本财政年度,我们编辑了一份关于其成就的报告,包括其出版物的清单。本报告已发送给相关领域的研究人员和本研究项目的成员。
英文摘要
This project addressed a question of how neural circuits are formed and functionally developed so as to execute the higher brain function. To elucidate mechanisms underlying the formation and functional development of neural circuits in the brain, we took multidisciplinary approaches in this project. Thus, a close collaboration among researchers with different methodologies was essential for success of this project. After such a collaboration among members of this research project, we succeeded in obtaining many excellent results which were published in top-rank international journals. In this fiscal year we have edited a report of their achievements including a list of their publications. This report has been sent to researchers who are working in related fields and the members of this research project.
期刊论文(83)
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会议论文
Kinoshita,S.,Yasuda,H.,Taniguchi,N.et al.: "Brain-derived neurotrophic factor prevents low-frequency inputs from inducing long-term depression in the developing visual cortex." J.Neuroscience. 19. 2122-2130 (1999)
Kinoshita,S.、Yasuda,H.、Taniguchi,N.等人:“脑源性神经营养因子可防止低频输入在发育中的视觉皮层中诱发长期抑郁。”
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通讯作者:
Allen, C., Jiang, Z., Teshima, K., Darland, T., Ikeda, M. et al.: "Orphanin-FQ (OFQ) modulates the activity of suprachiasmatic nucleus neurons"J. Neuroscience. 19. 2152-2160 (1999)
Allen, C.、Jiang, Z.、Teshima, K.、Darland, T.、Ikeda, M. 等人:“Orphanin-FQ (OFQ) 调节视交叉上核神经元的活动”J.
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Tsubokawa,H,,Oguro,K.,Robinsdon,H.P.C.,et al.: "Intracellular inositol 1,3,4,5-tetrakisphosphate enhances the calcium current in hippocampal CAl neurones of the gerbil followint transient forebrain ischaemia." J.Physiol.Lond.497. 67-78 (1996)
Tsubokawa, H,,Oguro,K.,Robinsdon,H.P.C.等人:“细胞内肌醇 1,3,4,5-四磷酸可增强沙鼠海马 CA1 神经元在短暂前脑缺血后的钙电流。”
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共 34 条
    Elucidation of mechanisms underlying involvement of neurotrophic factors in visual cortical plasticity using RNA interference
    Mechanisms underlying action of neurotrophic factors on postsynaptic glutamate and GABA receptors
    • 批准号:
      14208094
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $34.86万
    • 财政年份:
      2002
    • 负责人:
      TSUMOTO Tadaharu
    • 依托单位:
    DEVELOPMENT OF PHYSIOLOGICAL FUNCTION OF VISUAL CORTEX
    • 批准号:
      12210014
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas
    • 资助金额:
      $69.7万
    • 财政年份:
      2000
    • 负责人:
      TSUMOTO Tadaharu
    • 依托单位:
    Blocking action of neurotrophin on long-term depression in developing visual cortex
    • 批准号:
      09480241
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $8.32万
    • 财政年份:
      1997
    • 负责人:
      TSUMOTO Tadaharu
    • 依托单位:
    海外基金