Analysis of the mechanism of herbal medicines and identification of ingredients derived from herbal medicines for organ transplant rejection

治疗器官移植排斥的草药作用机制分析及草药成分鉴定

• 批准号: 15K19296
• 负责人: Uchiyama Masateru
• 金额: $ 1万
• 依托单位: Teikyo University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15K19296/
• 关键词: 移植免疫; 漢方薬; 漢方生薬; マウス; 心臓移植; 生着延長; 制御性T細胞; 拒絶反応

项目成果

A Japanese Herbal Medicine (TJ-21) Induced Generated Regulatory Cells and Prolonged Survival of Fully Allogeneic Cardiac Grafts in Mice

日本草药 (TJ-21) 诱导产生调节细胞并延长小鼠完全同种异体心脏移植物的存活时间

• 发表时间: 2017
• 期刊: Chinese Journal of Integrative Medicine
• 影响因子: 2.9
• 作者: Enzhi Yin;Masateru Uchiyama;Xiangyuan Jin;and Masanori Niimi
• 通讯作者: and Masanori Niimi

Enzhi Yin, Masateru Uchiyama, Takako Yanagisawa, Akira Inoue, Masanori Hara, Shigefumi Matsuyama, Tomohiro Imazuru, Masafumi Kawamura, and Masanori Niimi

Enzhi Yin、Masateru Uchiyama、Takako Yanagisawa、Akira Inoue、Masanori Hara、Shigefumi Matsuyama、Tomohiro Imazuru、Masafumi Kawamura 和 Masanori Niimi

• 发表时间: 2016
• 作者: Masateru Uchiyama;Xiangyuan Jin;Enzhi Yin;Takako Yanagisawa;Akira Inoue;Masanori Hara;Shigefumi Matsuyama;Tomohiro Imazuru;Hideo Yagita;Masafumi Kawamura;and Masanori Niimi;7 Components of Traditional Japanese Herbal Medicines Prolonged Survival of Fully Allogeneic Cardiac Grafts in Mice
• 通讯作者: 7 Components of Traditional Japanese Herbal Medicines Prolonged Survival of Fully Allogeneic Cardiac Grafts in Mice

Administration of Thrombomodulin (CD141) could improve cardiac allograft survival in mice

给予血栓调节蛋白（CD141）可以改善小鼠同种异体心脏移植物的存活率

• DOI: 10.1016/j.transproceed.2018.02.204
• 发表时间: 2018
• 期刊: Transplantation Proceedings
• 影响因子: 0.9
• 作者: Enzhi Yin;Shigefumi Matsuyama;Masateru Uchiyama;Michitaka Kono;and Masanori Niimi
• 通讯作者: and Masanori Niimi

Appetite Stimulation by Rikkunshito (TJ-43) Improved Reduction of Food Intake in Murine Cardiac Transplant Model

Rikkunshito (TJ-43) 的食欲刺激改善了小鼠心脏移植模型中食物摄入量的减少

• 发表时间: 2017
• 作者: Enzhi Yin;Masateru Uchiyama;Takako Yanagisawa;Akira Inoue;Masanori Hara;Shigefumi Matsuyama;Tomohiro Imazuru;Masafumi Kawamura;and Masanori Niimi
• 通讯作者: and Masanori Niimi

Glycyrrhizic acid in Licorice prolonged cardiac allograft survival in mice

甘草中的甘草酸可延长小鼠同种异体心脏移植物的存活率

• 发表时间: 2017
• 作者: Akira Inoue;Enzhi Yin;Masateru Uchiyama;Takako Yanagisawa;Masanori Hara;Shigefumi Matsuyama;Tomohiro Imazuru;Masafumi Kawamura and Masanori Niimi
• 通讯作者: Masafumi Kawamura and Masanori Niimi