Structural analysis of collagen fiber of arterial wall in patients with abdominal aortic aneurysm

肠系膜下动脉周围的腹主动脉外膜胶原纤维结构不成熟，L胶原纤维的中层方向随年龄的增长而趋于一致。此外，在腹主动脉瘤患者中，胶原密度显著降低。然而，与正常主动脉不同的是，AAA患者中层胶原方向分散，I型胶原体积减小。这些数据表明，AAA的形成不取决于部位的特异性和年龄，还取决于其他因素。

The structure of adventitial collagen fiber of abdominal aorta is immature around the inferior mesenteric artery and the direction of the media l collagen fiber becomes more identical in proportion to the age. In patients with abdominal aortic aneurysm, additionally, the collagen density is remarkably decreasing. However, differently from the normal aorta, the direction of medial collagen was scattered and the type I collagen decreases in volume in AAA patients. These data suggest that AAA formation does not depend on the site specificity and aging but also other factors.