Seroepidemiological Study on Adult T-cell Leukemia/Lymphoma in Papua New Guinea

巴布亚新几内亚成人T细胞白血病/淋巴瘤血清流行病学研究

• 批准号: 63042010
• 负责人: TERASHI Shin'ichi
• 金额: $ 3.58万
• 依托单位: KAGOSHIMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Overseas Scientific Survey.
• 财政年份: 1986
• 资助国家: 日本
• 起止时间: 1986 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63042010/
• 关键词: Monbusho International Scientific Research Program; Field Research; Special Cancer Research; Adult T-cell Leukemia; Lymphoma; Papua New Guinea; Viral Antibobies; Epidemiological survey

It is well known that Adult T-cell Leukemia/Lymphoma(ATL) is related to the infection of a kind of viruses and is observed in virus endemic areas(Southwestern Japan). Anti-ATL virus-assosiated antigen antibodies have been detected in the area of most patients and a reratevely high persentage of healthy individualas living in these areas. It is supposeed by epidemiological studies that the virus in transmitted by three main routes such as a blood transfusion, a mother to her children and a husband to his wife.The resultes was indicated Adult T-cell Leukemia/Lymphoma virus related-Antibodies were 251 out of 1,254 cases, or 20.0 % on average in Papua New Guinean sera.

成人t细胞白血病/淋巴瘤（Adult T-cell Leukemia/Lymphoma， ATL）与一种病毒的感染有关，并在病毒流行地区（日本西南部）观察到。在大多数患者和生活在这些地区的健康个体中检测到抗atl病毒相关抗原抗体的比例相对较高。流行病学研究认为，该病毒主要通过三种途径传播，即输血、母亲传染给孩子和丈夫传染给妻子。结果表明，1,254例成人t细胞白血病/淋巴瘤病毒相关抗体中有251例，在巴布亚新几内亚的血清中平均为20.0%。