Quantitative Evaluation of Hydrophilic-Hydrophobic Interaction in Amphiphilic Polymers

详细研究了含硅或氟原子的新型两亲性聚合物的自组装。采用小角x射线和中子散射技术对溶液中的聚合物聚集体进行了分析，并采用x射线反射率测量对空气-水界面处的聚合物单层进行了研究。一种梳状两亲性聚硅环丁烷（SB），具有亲水的聚氧乙烯侧链，可作为单个分子溶于甲醇或水中疏水SB与亲水性2-甲基丙烯酸羟乙酯（HEMA）组成的1:1嵌段共聚物或疏水聚苯乙烯与亲水性聚3-羟甲基硅环丁烷组成的1:1嵌段共聚物在甲醇中形成疏水核胶束。同样地，它们在甲苯中形成具有亲水核的反胶束。由SB和HEMA组成的1:1嵌段共聚物在水面形成均匀稳定的单层。一种水溶性乙烯醚嵌段共聚物，由短的不溶于水的氟化段和长的水溶性极性段组成，与非氟化嵌段共聚物相同，在水中形成核壳胶束。值得注意的是，含氟嵌段共聚物形成的胶束可以选择性地从含氟和非含氟水不溶性化合物的混合物中增溶含氟化合物。这些结果为评价两亲性聚合物的亲疏水相互作用提供了有用的重要信息。

Self-assembly of novel amphiphilic polymers containing silicon or fluorine atoms were investigated in detail. Small angle X-ray and neutron scattering techniques were employed for the analysis of the polymer aggregates in solution and X-ray reflectivity measurements were applied to the study of the polymer monolayers at the air-water interface. A comb-like amphiphilic polysilacyclobutane (SB) with hydrophilic polyoxyethylene side chains dissolved as a single molecule in methanol or water. contrast, a 1 : 1 block copolymer composed of hydrophobic SB and hydrophilic 2-hydroxyethyl methacrylate (HEMA) or a 1 : 1 block copolymer composed of hydrophobic polystyrene and hydrophilic poly (3-hydroxymethylsilacyclobutane) formed micelles with hydrophobic core in methanol. Similarly they formed reversed-micelles with hydrophilic core in toluene. A 1 : 1 block copolymer composed of SB and HEMA formed uniform and stable monolayer at the water surface. A water-soluble vinyl ether block copolymer consisting of a short water-insoluble fluorinated segment and a long water-soluble polar segment formed core-shelled micelles in water as in the same way of non-fluorinated block copolymers. It is worth noting that the micelles formed by the fluorine-containing block copolymer could selectively solubilize fluorinated compounds from the mixture of fluorinated and non-fluorinated water-insoluble compounds. These results provided useful and important information for the evaluation of the hydrophilic-hydrophobic interaction of amphiphilic polymers.