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Research for Confirming the Diagnostic Criteria and the Diagnostic Methods of Pulmonary Nodules Depicted by Lung Cancer Screening Using Helical CT.

螺旋CT肺癌筛查诊断肺结节的诊断标准和诊断方法的研究。

基本信息

批准号：
09670934
负责人：
HIROTA Shozo
金额：
$ 1.66万
依托单位：
KOBE UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1998
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09670934/
关键词：
Helical CT Lung cancer Screening Diagnostic criteria Diagnostic method

项目摘要

From 1991 to 1998, the secondary screening for lung cancer by helical CT has been performed in 801 persons. In 82 out of 801 cases, pulmonary nodules were depicted (primary lung cancer : 24 cases, metastatic tumor 9 cases, benign lesion 49 cases). To confirm the diagnostic criteria for the screening these helical CT findings and HRCT findings were analyzed, and from the results, three plans for diagnostic criteria were discussed.In cases of nodules smaller than 5mm in diameter, the majorities were benign, and the larger nodular size was, the more malignant tumor was increased. And in cases of primary lung cancer, lobulation, spiculation, pleural indentation, vascular involvement (especially PV) and solid density were often found in helical CT.These CT findings were more often found in HRCT.In cases of metastatic tumor, it was only larger number of the lesions in helical CT, but in HRCT, solid density and lobulation were often found.In conclusion, it was suggested that in cases of larger than 5mm in diameter, if one of these findings of suspected malignancy was seen, further examination should be done. In cases of nodules smaller than 5mm in diameter, if round shape, well difined and smooth margin were seen, the nodule was suspected to be benign, and observation would be needed.

1991年至1998年，已对801人进行了螺旋CT肺癌二次筛查。 801例中，82例出现肺部结节（原发性肺癌24例，转移性肿瘤9例，良性病变49例）。为了确定筛查的诊断标准，对这些螺旋CT表现和HRCT表现进行了分析，并根据结果讨论了三种诊断标准方案。结节直径小于5mm的情况下，大多数为良性，结节尺寸越大，恶性肿瘤越多。而对于原发性肺癌，螺旋CT常出现分叶状、毛刺状、胸膜凹陷、血管受累（尤其是PV）和实性密度。这些CT表现在HRCT中较多见。对于转移性肿瘤，螺旋CT仅是病灶数量较多，而HRCT常出现实性密度和分叶状。综上所述，建议在肿瘤较大的病例中，螺旋CT仅发现病灶数量较多。直径大于5毫米，如果发现其中一项疑似恶性肿瘤，应进一步检查。直径小于5毫米的结节，如发现结节呈圆形、界限清楚、边缘光滑，则怀疑结节为良性，需观察。

项目成果

期刊论文数量（14）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

本山新.楠本昌彦.糸氏英一郎.足立秀治.河野通雄:他5名: "ヘリカルCTの肺癌2次検診への応用-5年間の要精検例のCT所見の分析-" 胸部CT検診. 4(3). 148-151 (1997)

Arata Motoyama、Masahiko Kusumoto、Eiichiro Itoji、Hideharu Adachi、Michio Kono：等 5 人：“螺旋 CT 在肺癌二次筛查中的应用 - 需要详细检查的病例的 5 年期间 CT 表现分析 -”胸部 CT 筛查4（3）。148-151（1997）。