Left Ventricular Reduction Cardiomyoplasty

背景。几项使用双侧背阔肌降低左室心肌成形术的实验研究并没有获得对衰竭心脏足够的辅助，也没有与单次心肌成形术相比明确的估计。在本研究中，我们的双次心肌成形术与单次心肌成形术相比显示出优越的疗效。心脏和心脏的后面直接相互缝合。静脉给予心得安诱导急性心力衰竭，测量双侧背阔肌辅助下的血流动力学变化后，对同一只狗进行单次心肌成形术。结果。通过我们的双心肌成形术，收缩期主动脉压（AoP）增加24% (p<0.001)，收缩期肺动脉压（PAP）增加40% (p<0.001)，收缩期末期弹性（Ees）增加155% (p<0.001)，心输出量（CO）分别增加55% （p<0.001）。AoP、PAP、Ees、SV明显增高。与单次心肌成形术相比结论。本研究表明，与单一心肌成形术相比，我们的左室降低心肌成形术提供了显著的血流动力学改善。

Background. Several experimental studies on LV reduction cardiomyoplasty using the bilateral latissimus dorsi muscles were not acquired sufficient assist to the failing heart and were not estimated clearly compared with single cardiomyoplasty, In this study, a superior efficacy of our double cardiornyoplasty method was shown, compared with single cardiomyoplasty. the heart and directly sutured to each other behind the heart. Acute heart failure was induced by administering propranolol intravenously, After the hemodynamic changes with bilateral latissimus dorsi muscles assistance were measured, single cardiomyoplasty was done in the same dog. Results. By our double cardiomyoplasty, systolic aortic pressure (AoP) increased by 24 % (p<0.001), systolic pulmonary artery pressure (PAP) by 40 % (p<0.001), end-systolic elastance (Ees) by 155 % (p<0.001), and cardiac output (CO) by 55 % (p<0.001) respectively. There were clearly significant increases in AoP, PAP, Ees, SV.and CO by our double cardiomyoplasty compared with single cardiomyoplasty. Conclusion. This study demonstrated that our LV reduction cardiomyoplasty provided significant hemodynamic improvement in comparison with single cardiomyoplasty.