权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Endocardioscope for repair of an atrial septal defect under the beating heart

心内镜在心脏跳动下修复房间隔缺损

基本信息

批准号：
09671367
负责人：
OHZEKI Hajime
金额：
$ 0.38万
依托单位：
Niigata University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1998
项目状态：
已结题

项目摘要

The purpose of this study was to evaluate the possibility of surgical treatment of an atrial septal defect in the beating heart without cardiopulmonary bypass. The first step was to develop an endocardioscope that permitted observation of the inside of the beating heart. To visualize the inside of the beating heart, the tip of the endoscope was covered with a glass adapter. The endocardioscope was inserted through the right atrial appendage in eight beagles. The atrial septum, foramen ovale, coronary sinus, tricuspid valve, and chordae tendineae were identified without hemodynamic derangement. The second step was to attempt to close the foramen ovale with clips or staplers. We were able to close the foramen ovale with these devices, but a safer, easier device is needed. The endocardioscope we developed should prove to be a useful tool for minimally invasive surgical treatmnet of heart diseases, such as atrial septal defect.

本研究的目的是评估在心脏不停跳下非体外循环手术治疗房间隔缺损的可能性。第一步是开发一种可以观察跳动的心脏内部的心内镜。为了观察跳动的心脏内部，内窥镜的尖端覆盖有玻璃适配器。通过右心耳插入8只比格犬的心内镜。房间隔、卵圆孔、冠状窦、三尖瓣和腱索被识别，无血流动力学紊乱。第二步是尝试用夹子或吻合器闭合卵圆孔。我们能够用这些器械闭合卵圆孔，但需要一种更安全、更容易的器械。我们研制的心内镜应被证明是一种有用的工具，微创外科治疗心脏疾病，如房间隔缺损。