Experimental thoracoscopic tracheal and bronchial anastomosis, and how to control the pulmonary malignancy by thoracoscopic surgery

实验性胸腔镜气管支气管吻合术及胸腔镜手术控制肺部恶性肿瘤

基本信息

  • 批准号:
    09671369
  • 负责人:
  • 金额:
    $ 1.73万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 财政年份:
    1997
  • 资助国家:
    日本
  • 起止时间:
    1997 至 1998
  • 项目状态:
    已结题

项目摘要

(1) We assessed an application of a skin stapler for tracheal anastomosis experimentally in dogs. Sections of cervical trachea covering 5 rings from 2.4 cm to 3.5 cm in length were excised and anastomosis was performed by skin stapler in group 1 (n= 10) and by resorbable 4-0 suturing in group 2(n= 10). After 6 months, all animals harvested and observed anastomotic site macroscopically and microscopically. Histological examination of the anastomotic sites in all animals revealed normal tracheal epithelium covering. Tracheal anastomosis by stapler is possible and the same as hand-sewn in the short-term experimentally.(2) The safety and efficacy of video-assisted thoracoscopic surgery (VATS) for metastatic lung disease was study retrospectively. Between January 1993 and December 1996, we performed pulmonary wedge resection by VATS for metastatic lung tumors in twenty-one patients (19 male, 10 female : A group). Between January 1987 and January 1990, we performed pulmonary wedge resection on 21 patients (14 male, 7 female : Open group) with metastatic pulmonary disease via a middle sternal-splitting approach or lateral thoracotomy. Median survival was 28.9 months for the Open group and 37.9 months for the VATS group. Actuarial survival was not significantly different for the two groups. Thus the type of approaches did not affect survival following metastasectomy.(3) A microwave generator and delivery system for metastatic pulmonary tumor was designed. Using this probe for pulmonary tumor was easy to controlled coaglation form lung parenchyema.(4) Pericutaneous cutting needle biopsy under the thoracoscope were presented. This thoracoscopic cutting needle biopsy was easy to obtain a specimen for the frozened section diagnosis. Under the view of thoracoscope, pericutaneous cuting needle biospy is safty, saving the cost for staples and easy to control the bleeding from the lung.
(1) 我们通过实验评估了皮肤吻合器在犬气管吻合术中的应用。切除颈部气管切片,覆盖5个长度为2.4 cm至3.5 cm的环,第1组(n = 10)采用皮肤吻合器进行吻合,第2组(n = 10)采用可吸收4-0缝合进行吻合。 6个月后,收获所有动物并进行宏观和微观观察吻合部位。所有动物的吻合部位的组织学检查显示正常的气管上皮覆盖。吻合器气管吻合在短期实验中是可行的,与手工缝合相同。(2)回顾性研究电视辅助胸腔镜手术(VATS)治疗转移性肺疾病的安全性和有效性。 1993年1月至1996年12月期间,我们对21名转移性肺肿瘤患者(19名男性,10名女性:A组)进行了VATS肺楔形切除术。 1987年1月至1990年1月期间,我们通过胸骨中劈入路或侧开胸手术对21名患有转移性肺疾病的患者(14名男性,7名女性:开放组)进行了肺楔形切除术。开放组的中位生存期为 28.9 个月,VATS 组的中位生存期为 37.9 个月。两组的精算生存率没有显着差异。因此,方法的类型不会影响转移瘤切除后的生存。(3)设计了用于转移性肺肿瘤的微波发生器和传输系统。使用该探针对肺部肿瘤进行控制,易于从肺实质中进行电凝。(4)提出了胸腔镜下经皮切针活检。这种胸腔镜切针活检很容易获得标本用于冰冻切片诊断。胸腔镜下经皮切针活检安全,节省缝钉费用,易于控制肺部出血。

项目成果

期刊论文数量(22)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
S.Sugiyama, et al.: "Internal jugular vein malformation with mature adipose deposits in the mediastinum" Surg Today, Jpn J Surg. 28. 455-458 (1998)
S.Sugiyama 等人:“纵隔内伴有成熟脂肪沉积的颈内静脉畸形”Surg Today,Jpn J Surg。
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Sugiyama, S, et al: "Thoracoscopic cutting needle biopsy for lung tumors" 6th World Congress of Endoscopic Surgery. 6. 1191-1194 (1998)
Sugiyama, S 等人:“胸腔镜下肺部肿瘤切针活检”第六届世界内窥镜外科大会。
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Sugiyama S,et al: "Thoracoscopic cutting needle biopsy for lung tumors" 6th World Congress of Endoscopic Surgery. 6. 1191-1194 (1998)
Sugiyama S,et al:“胸腔镜下肺部肿瘤切针活检”第六届世界内窥镜外科大会。
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Y.Mizushima,S.Sugiyama,: "Prognosis for patients with pneumonectomy or lesser resections for non-small cell lung cancer based on histologic cell type" Oncology Reports. 5. 689-692 (1998)
Y.Mizushima,S.Sugiyama,:“根据组织学细胞类型对非小细胞肺癌进行全肺切除术或较小切除术的患者的预后”肿瘤学报告。
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S.Sugiyama, et al.: "A Dumon stent inserted for Bronchial stenosis causing a left brpnchial fistula : report of a case" Surg Today, Jpn J Surg. 28. 1091-1094 (1998)
S.Sugiyama 等人:“插入 Dumon 支架治疗支气管狭窄导致左支气管瘘:病例报告”Surg Today,Jpn J Surg。
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SUGIYAMA Shigeki其他文献

SUGIYAMA Shigeki的其他文献

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