Secretion of the airway cilliated epithelial cell

呼吸道分泌物的来源被认为是由浆液腺、杯状细胞、毛细血管渗出物和白细胞的细胞碎片组成。我们首次用膜片钳技术证实了豚鼠气管纤毛上皮细胞给予β-肾上腺素能、胆碱能和嘌呤能激动剂后，氯离子电导增加。我们认为，纤毛跳动的低黏性周围层可能部分是由纤毛上皮细胞本身形成的。

The Origin of airway secretion are thought to be composed of seromucous glands, goblet cells, transudation from capillaries secretions and cell debris from leucocytes. We demonstrated that the chloride conductance of tracheal ciliated epithelial cells excised from guinea pigs increases after administration of β-adrenergic, cholinergic and purinergic stimulants based on the patch clamp technique for the first time. We concluded that the pericilliary layers with low viscosity in which cilia beat is possibility formed partly by the ciliated epithelial cell itself.