Bioorganic Chemical Studies for Biorational Pest Control

生物合理害虫防治的生物有机化学研究

• 批准号: 59430021
• 负责人: MIZUTANI Junya
• 金额: $ 21.06万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (A)
• 财政年份: 1984
• 资助国家: 日本
• 起止时间: 1984 至 1986
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-59430021/
• 关键词: Biorational Pest Control; Plant Growth Inhibitors; Fungitoxic Substances; Cyclopentanoid Sesquiterpenes; <gamma> -Glutamyl Peptides; Canavanine; Isoflavones; ファイトアレキシン; 植物病原菌; γ-Glu誘導体; 自己防衛的能力

1. Hirsutin ( <1!wave> ), a mustard oil of Rorippa sylvestris (Cruciferae) exhibited the plant growth inhibitory activity. We investigated the structure-activity relationships of <1!wave> and related compounds (29 compounds in all), and it has been shown that <1!wave> may be a lead compound for the development of herbicides. Lichenic acids (3 phenolic acids and 6 depsides) isolated from Usnea spp. (Lecanorales) showed the plant growth inhibitory activity.2. New fungitoxic cyclopentanoid sesquiterpenes (6 compounds), new oxidized C-18 unsaturated fatty acids (6 compounds), oxidized C-9 <to> C-11 fatty acids and hydroxydi-hydrobovolide have been isolated from timothy choke caused by Epichloe typhina. Antifungal, and plant seed germination and growth inhibitory activities of these compounds were tested. The timothy plant infected by E. typhina has been found to be resistant against another timothy leaf spot disease pathogen, Cladosporium phlei, and the resistant mechanism was discussed in … More connection with these antifungal compounds. The above-mentioned compounds were also suggested to cause the inhibition of coming into ears of the infected timothy plants.3. Eight <gamma> -glutamyl peptides were isolated from the bulbs of Allium bakeri (Liliaceae). The canavanine content of alfalfa seeds rather increased during germination contrary to the knowledge from literature. The insecticidal and antimicrobial activities of <gamma> -glutamyl peptides, canavanine and related compounds were tested, but no compounds were found to show remarkable activities.4. New complex isoflavones (6 compounds), coumaronochromones (6 compounds) and 5-o-methylisoflavones (5 compounds) were isolated from yellow and white lupins. Five pterocarpans including one new compound and new four 3-hydroxyflavanones as phytoalexins were found in two species (Leguminosae), respectively. Furthermore, metabolic pathways of fungitoxic prenylated isoflavones by fungi were studied, and it was suggested that the chemical defense mechanism against pathogens in the lupins might be broken down through the detoxification of antifungal compounds by fungi. Less

1.水飞蓟素(&lt；1！Wave&gt；)是一种十字花科植物芥子油，具有抑制植物生长的活性。我们研究了~lt；1！Wave&gt；及其相关化合物(共29个化合物)的构效关系，结果表明~lt；1！Wave&gt；可能是开发除草剂的先导化合物。松茸中的地衣酸(3种酚酸和6种多酚)。(Lecanorales)表现出抑制植物生长的活性。从斑节油菜(Epichloe Typhina)引起的Timothy Check中分离得到了新的真菌氧基环戊烷倍半萜(6个化合物)、新的氧化C-18不饱和脂肪酸(6个化合物)、氧化C-9和C-11脂肪酸以及羟基二氢呋喃。对化合物的抗真菌活性、植物种子萌发和生长抑制活性进行了测试。侵染伤寒病菌的蒂莫西植株对另一种蒂莫西叶斑病病原菌具有抗性，并在…中对其抗性机制进行了讨论。与这些抗真菌化合物有更多的联系。上述化合物还可抑制受侵染的Timothy植株的入穗。从百合科大葱的鳞茎中分离得到8个谷氨酰基肽。与文献报道相反的是，在发芽过程中，紫花苜蓿种子中的刀豆碱含量有所增加。对~lt；γ&Gt；-谷氨酰多肽、刀豆碱及相关化合物进行了杀虫、抑菌活性测试，未发现有明显活性的化合物。从黄羽扇豆和白羽扇豆中分离得到新的复杂异黄酮(6个化合物)、香豆素(6个化合物)和5-O-甲基异黄酮(5个化合物)。从豆科2种植物中分离得到5个蕨类化合物，其中包括1个新化合物和4个新的3-羟基黄烷酮类化合物。此外，还研究了真菌对真菌毒性戊烯基异黄酮类化合物的代谢途径，认为羽扇豆苷中对病原菌的化学防御机制可能是通过真菌对抗真菌化合物的解毒来实现的。较少

项目成果

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铃木肯：农业.生物.化学.51。

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田原聪：“异戊二烯化异黄酮甘草异黄酮 A 的真菌代谢。”

INGHAM,John L.: J.Nat.Prod.49. 631-638 (1986)

约翰·L·英厄姆：J.Nat.Prod.49。

INGHAM, John L.: "Isoneorautenol and Other Pterocarpan Phytoalexins from Calopogonium mucunoides." Z. Naturforsch.40c. 482-489 (1985)

INGHAM, John L.：“来自 Calopogium mucunoides 的异松黄烯醇和其他紫檀植物抗毒素。”

INGHAM, John L.: "A Chemical Investigation of Pueraria mirifica Roots." Z. Naturforsch.41c. 403-408 (1986)

约翰·L·英厄姆：“野葛根根的化学研究”。