Role of hemolymoh on metabolism, immune systems and endocrine systems in insects.

研究了血淋巴蛋白的生物合成、代谢、在特定组织中的积累以及血淋巴蛋白的生理作用，包括卵黄蛋白原、卵子特异蛋白、前酚氧基酶和杀菌蛋白。还研究了昆虫激素对这些蛋白质合成和激活的作用，以及通过血淋巴调节激素效价的作用。本研究对家蚕肉质中的一种杀菌蛋白和家蚕基因中的30 KDa蛋白的DNA序列进行了广泛的研究。明确了卵特异蛋白在家蚕胚胎发育过程中的去向。对蜕皮激素和其他类固醇在卵黄发生中的作用进行了研究，并对蜕皮激素通过血淋巴的滴度控制机制提供了可能的数据。此外，还发现一些蛋白多糖受体参与了原酚氧化酶的激活，这可能在昆虫的免疫系统中发挥重要作用。

Biosynthesis, metabolism, accumulation into particular tissues and physiological action of hemolymph protein, including vitellogenin, eggspecific protein, prophenoloxydase and bacteriocidal proteins, were studied. Action of insect hormones on the synthesis and activation of these proteins, and regulation of hormonal titer through hemolymph were also studied. In this research project, DNA sequences of a bacteriocidal protein in the fleshlfy and 30 KDa protein in silkworm gene were extensively studied. Fate of egg-specific protein in developing embryo of the silkworm was clarified. Role of ecdysone and other steroids on vitellogenesis was studied and suggestive data were obtained on the control mechanisms of ecdysone titer through hemolymph.I was found also that some kind of receptors of proteoglycan was involved in activation of prophenoloxidase which might play an important role on immune systems in insects.