200kV Cyro-Transmission Electron Microscope

200kV 冷冻透射电子显微镜

• 批准号: 520852391
• 金额: --
• 依托单位: Universität Stuttgart
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2023
• 资助国家: 德国
• 起止时间: 2022-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/520852391?language=en
• 关键词: 200kV; Cyro; Transmission; Electron; Microscope

The interfaculty research network SRF AMICA (Stuttgart Research Focus Advanced Materials Innovation and Characterization) pools the instrumental, methodological and technical expertise of various scientists at the University of Stuttgart and strengthens the collaboration between scientists of different research areas. The planned transmission electron microscope will be operated as a multi-user instrument within the framework of the AMICA core facility and will thus be available to all users of the university. It will replace one irreparably defective and three outdated transmission electron microscopes. This will bring together further expertise in the field of transmission electron microscopy in a joint research center. High-resolution characterizations of beam-sensitive materials by transmission electron microscopy are essential and state of the art for current research areas in biology, biomedicine, chemistry and materials science. For the adequate characterization of beam-sensitive samples (especially with cryo- and tomography methods), there is currently no suitable equipment available at the University of Stuttgart - despite the existing need - especially not for the broad application in user mode. The application for the Cryo-sTEM is intended to meet this need and to ensure easy access to the method via AMICA. The selected instrument configuration requested here meets the requirements for a variety of different participating research groups. Beam-sensitive materials of current and planned research projects to be investigated with the planned Cryo-sTEM include biogenic materials, biominerals, viruses, DNA/RNA nanostructures, mammalian cells, muscle tissue, polymers, hydrogels, plastics and hybrid materials. The research questions and projects range from biology and biomedicine to chemistry, materials science and a number of interdisciplinary and cross-faculty research projects.

跨教职研究网络SRF AMICA(斯图加特研究聚焦先进材料创新与表征)汇集了斯图加特大学不同科学家在仪器、方法和技术方面的专业知识，加强了不同研究领域的科学家之间的合作。计划中的电子显微镜将作为阿米卡核心设施框架内的多用户仪器使用，因此将向大学的所有用户提供。它将取代一台有不可修复的缺陷和三台过时的透射电子显微镜。这将在一个联合研究中心汇聚透射式电子显微镜领域的进一步专业知识。对于当前生物学、生物医学、化学和材料科学领域的研究领域，利用透射式电子显微镜高分辨率表征光束敏感材料是必要的和最先进的。为了充分表征光束敏感样品(特别是冷冻和层析成像方法)，斯图加特大学目前没有合适的设备--尽管现有的需要--特别是不适合在用户模式下广泛应用。低温茎的申请旨在满足这一需求，并确保通过AMICA轻松访问该方法。此处要求的选定仪器配置符合各种不同参与研究小组的要求。目前和计划中的低温研究项目将研究的束流敏感材料包括生物材料、生物矿物、病毒、DNA/RNA纳米结构、哺乳动物细胞、肌肉组织、聚合物、水凝胶、塑料和杂化材料。研究问题和项目范围从生物学和生物医学到化学、材料科学和一些跨学科和跨院系的研究项目。