A study of cross-sectional anatomy in neonatal ane fetal period as a fundamental knowledge for two-dimensional echocardiography

二维超声心动图是一种有效的无创诊断先天性心脏病的方法。随着新生儿重症先心病急诊无导管手术数量的增加，需要对畸形心脏进行详细、正确的了解。我们将用冷冻切片技术制作的大鼠新生心脏的多个横切面与人类新生儿的二维超声心动图图像进行了比较。用这种方法对心脏内和心脏周围各部分的结构进行了识别。在此基础上，提出了用相同的方法鉴定大鼠胎心横切面的方法。因此，在新生儿和胎儿心脏中进行详细的解剖鉴定是可能的。子宫内二维超声心动图正确诊断完全性心内膜垫缺损1例。

Two-dimensional echocardiography is a useful method for noninvasive diagnosis of congenital heart disease. As the number of emergency operation without catheterization for new born patients with severe congenital heart disease has been increased, the detail and correct information about the malformed heart is required. We compared multiple cross-sections of the new born heart of rat, which was made using a frozen section technique, with the image of two-dimensional echocardiography in human neonates. Each portion of intra and peri-cardiac structure was identified by this method. Then we advanced to identify cross-section of fetal heart of rat by using the same technique. As a results, detailed anatomical identification has been possible in a neonatal and fetal heart. A case with complete endocardial cushion defect was correctly diagnosed by two-dimensional echocardiography in utero.