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An application of magnetic liquid for continent colostomy.

磁性液体在大陆造口术中的应用。

基本信息

批准号：
60570586
负责人：
YAMAGUCHI Takaji
金额：
$ 1.15万
依托单位：
Hamamatsu University School of Medicine
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1985
资助国家：
日本
起止时间：
1985 至 1986
项目状态：
已结题

项目摘要

Magnetic liquid has been watched with keen interest in technology as a new material, but it's usufulness is not found in medical field.Continet colostomy with the aid of a magnetic tightening system was designed to evaluate the functional results. The principle of our method is to tighten the stoma by the magnetic force originated between a magnetic cup inserted into the stoma and the magnetic liquid implanted around the colon.Apparatus ; The magnetic system consists of two parts, a torus bag like a doughnut ( made of silicone rubber, supplied by KOKEN ) which is filled with dextran-magnetite sol ( magnetic liquid, supplied by MEITO SANGYO ) and a magnetic cap with a central pin ( supplied by TOSHIBA ).Experimental Study ; Two step experiments were performed. Initially the continent ability of the stoma and the frequency of complications with this new method were examined using five mongrel dogs, which were colostomized and implanted with magnetic liquid. There were three major complications such as sepis due to stomal infections, severe skin erosion and stenosis of the stoma.Next project was performed to evaluate the function of the magnetic stoma using 10 beagle dogs. Meticulous daily care and treatment of the stoma have been taken by vertinary surgeons in three month. The magnetic cap was inserted into the stoma during 8 hours per day in each dog.The stoma was continent if the magnetic energy was strong enough ( BH max : 15 MGOe ), but below 5 MGOe incontinence was occurred. There were no infections nor stomal necrosis, but slight stenosis at the position of implant were occurred frequently due to the reduction of compliance.From these results, it is concluded that the magnetic stoma system using magnetic liquid is effective and attractive for the colostomy, but it has some room for more improvement.

磁性液体作为一种新材料，在技术上受到了极大的关注，但它在医学领域的应用还不多见。我们的方法的原理是利用插入吻合口的磁杯和植入结肠周围的磁性液体之间的磁力来收紧吻合口。装置；磁性系统由两部分组成，一个环形袋(由硅橡胶制成，由Koken公司提供)，其中填充葡聚糖-磁铁矿溶胶(磁性液体，由MEITO Sangyo提供)和一个带中心销的磁帽(由东芝公司提供)。用5只杂种犬进行造口并植入磁性液体，初步检测造口的可控性和并发症的发生率。术后出现3种主要并发症：造口感染所致的脓毒症、严重的皮肤侵蚀和造口狭窄。接下来，我们用10只比格犬对磁性造口进行功能评估。在三个月的时间里，垂直外科医生对造口进行了细致的日常护理和治疗。每只犬每天8h将磁帽置入吻合口，当磁场能量足够强时(BHmax：15mGOe)，吻合口呈可控性，但在5mGOe以下出现尿失禁。无一例发生感染和造口坏死，但因顺应性降低，植入物部位常出现轻度狭窄，说明磁性液体造口系统是一种有效、有吸引力的造口方法，但仍有一定的改进空间。