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STUDIES FOR THE ESTIMATION PROCEDURE ON THE QUALITY OF ALISMATIS RHIZOMA

泽泻品质评价方法的研究

基本信息

批准号：
61571016
负责人：
IDA Yoshiteru
金额：
$ 1.47万
依托单位：
Showa University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1986
资助国家：
日本
起止时间：
1986 至 1988
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-61571016/
关键词：
Alismatis Rhizome Alisma orientale triterpene diterpene Alismatis Rhizome Alisma orientale triterpene diterpene sesquiterpene 澤瀉成分研究 Alismatis Rhizoma Alismatis orientale Alismataceae protostane guaian triterpen alisol /

项目摘要

The purpose of this studies is to establish a chemical estimation procedure of the quality of commercial Alismatis Rhizomes, which are inported from several countries in Asia such as China, Korea, Taiwan, etc, and it has been said that the qualities of the crube drugs are different and depend on their districts. The studies were carried out as follows.(1) The phytochemical investigation on the crude drugs cultivated in Japan : seventeen components including eight new compounds were isolated and characterized.(2) The phytochemical invcestigation on the crude drugs inported from China(cultivated in Szechwan) : sixteen components including five new compounds were isolated and characterized.(3) The phytochemical investigation on fresh rhizomes of Alisma orientale cultivated in Wakayama-ken : twenty components including four new compounds were isolated and characterized.(4) A general chromatographic technique for the quantitative analysis of alisols of ptotostane type triter penoid in the crude drug were established.(5) The quatities of four majour alisols in the various crude drugs available in the Japanese market were estimated by means of the procedure established above. The contents of alisols were remarkable different among crude drugs from different districts.

本研究的目的是建立一种化学评价方法，以评价从亚洲几个国家如中国、韩国、台湾等进口的商品泽泻的质量。研究进行如下。(1)对日本栽培的生药进行了植物化学研究：共分离鉴定了17种成分，其中包括8个新化合物。(2)对川产进口药材的化学成分研究：共分离鉴定了16个成分，其中5个为新化合物。(3)对日本和歌山县栽培的泽泻（Alisma orientale）新鲜根茎的化学成分进行了研究：共分离鉴定了20个化合物，其中包括4个新化合物。(4)建立了泽泻醇类成分的色谱分析方法。(5)用上述方法测定了日本市场上各种药材中四种主要泽泻醇的含量。不同产地药材中泽泻醇含量差异显着。