日本人の寿命、疾病発症と遺伝環境の因子効果に関する比較衛生学的研究

我们用原始的健康风险评估程序分析了各种医学检查的结果。该节目是根据日本人的流行病学数据制作的。总的来说，患成人疾病的风险与饮酒或吸烟等基本生活习惯有关，我们再次确认它们对我们健康的不良影响的重要性。实践证明，健康风险评估体系与个体体系相结合，在延长生命和预防疾病方面是有效的，要想取得良好的实际效果，必须对每个风险项目建立适当的观察期。对胸围身高的回归分析表明，回归的贡献系数约为0.55。因此，即使对正常体型的人来说，额外测量他们的腹围对于早期发现健康障碍也很重要。日本吸烟者的相对比例低于韩国。相反，日本每天吸烟超过21支的烟民比例更高。日本人淋巴细胞免疫遗传特征的实验揭示了年龄对t细胞亚群分布的影响。日本人的HLA（Human leukocyte Antigen，人白细胞抗原）的组成呈现出很有特色的模式。例如，在一类抗原HLA-A抗原中，A2和A24的出现率远远高于其他抗原。这个事实对于器官移植非常重要，因为A2抗原的匹配在供体和受体之间非常重要。日本人被证明具有一些典型的HLA模式，包括连锁不平衡。

We analyzed results of various medical examinations by our original health risk appraisal program. The program was made on epidemiological data of Japanese people. On the whole, the risk of having adult diseases was related to fundamental life practice such as drinking or smoking, and we reconfirm the importance of their bad influence on our health.It was proved that the combination of the health risk appraisal system and individual systems are effective in prolonging life and preventing diseases, and that establishment of proper observation period is necessary for every risk item to get good practical results.The regression analysis of vental girth by height proved that the contribution coefficient of regression is about 0.55. It is therefore suggested even to people of normal build that additional measurement of their vental girth is important for early detection of health disorder.The relative percentage of smokers were lower in Japan than in Korea. Instead the percentage of smokers who take more than 21 cigarettes a day were higher in Japan.Experiments on immuno-hereditary characteristics of Japanese people with human lymphocyte revealed effects of aging on the distribution of T-cell subsets. And the composition of HLA(Human Leucocyte Antigen) in the Japanese showed very characteristic pattern. For instance, in HLA-A antigen, one of class I antigens, the appearance ratio of A2 and A24 were much higher than that of other antigens. The fact is very important on organ plantations, because the matching of A2 antigen is important between a donor and a recipient. Japanese people proved to have some characteristic pattern of HLA including linkage disequilibrium.