Study on virus vectors in silkworm

杆状病毒已被用作在已建立的细胞系和家蚕幼虫中表达干扰素、半乳糖苷酶和干扰素的载体。用电子显微镜研究杆状病毒在培养细胞中的增殖。Bombyx DNV-2是另一个候选的病毒载体，它有两个基因组DNA(DNA I和DNA II)。用几种限制性内切酶对DNA I和DNA II进行切割，构建了DNA I和DNA II图谱。这些图谱表明DNA I和DNA II是不同的。

Baculoviruses has been used previously as vectors for expression of -interferon, -galactosidase and -interferon in established cell lines and in silkworm larvae. Maltiplication of baculovirus in cultured cells was studied with a electrone microsope. Bombyx DNV-2 which is another candidate of the virus vector has two genomic DNAs (DNA I and DNA II). the maps of DNA I and DNA II have been constructed by cleaving it with several restriction endonucleases. These maps show that DNA I and DNA II are distinct.