Study on the effects of CO2 LASER for the articular cartilagy.

CO2激光对关节软骨影响的研究。

• 批准号: 62570697
• 负责人: INOUE Kazuhiko
• 金额: $ 1.02万
• 依托单位: Institute of Rheumatology. Tokyo women's medical college
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-62570697/
• 关键词: CO2 LASER; low pawer LASER; Osteoarthritis; 炭酸ガスレーザー; YAGレーザー; アルゴン; ダイレーザー

1. there ore three kinds of LASER, CO2 LASER, YAG LASER and Argon-dye LASER, fora medical use, CO2 LASER is most suitable for the treatment of degenerative articalor cartilage occording to its characteristics. Because, CO2 LASER is an infrared rays and 90% of its energy is absorbed on a surface of any kind of materials. And,CO2 LASER is effective for the degenerative articalor cortilage by the photo-chemical and thermal effects, However, YAG LASER and Argon-dye LASER is reflected on the surfal of the milky-white articalar cartilage according to the characteristics of visible rays.2. The animal study was performed using rabbits and dogs. On the power of CO2 LASER, over 5w, thermal damage was Occured by the exposure of CO2 LASER. So low pawer about 500mW is good for the treatment of degenerative articulor cartilage. For the rebbits knee, CO2 LASER ezposure in 500mW, 10 second , was done by the arthrotomy. After one to twelve weeks, the articulor cartilage was examined macroscopically and histologi cally. There is no adounce of degenerative change of articular cartilage in CO2 LASER exposed area. By the use of arthroscopy. changes of articalar cartilage was observed in dog's knee. There is no change in the articular cartilage arthroscopically in the period of one year. Also, there is no change in the articular caltilage histrogically.3. In the clinical study, the articular cartilage was observed arthroscopically one year after the exposure of CO2 LASER. There is no change in color and softness of the LASER exposured articular cartilage

1.激光有CO_2激光、YAG激光和氩染料激光三种，在医用方面，CO_2激光因其自身特点最适合于关节软骨退变的治疗。因为CO2激光是一种红外线，其90%的能量被任何一种材料的表面吸收。CO_2激光通过光化学和热效应对退变的关节软骨有效，而YAG激光和氩染料激光则根据可见光的特点反映在乳白色的关节软骨表面.使用兔和犬进行动物研究。当CO_2激光功率大于5 W时，激光辐照引起热损伤。因此，500 mW左右的低功率激光对退行性关节软骨的治疗是有利的。对于Rebits膝关节，通过关节切开术进行500 mW，10秒的CO2激光治疗。术后1 ~ 12周，对关节软骨进行大体和组织学检查。CO_2激光照射区关节软骨无明显退变。通过关节镜的使用。观察犬膝关节软骨的变化。一年内关节镜下关节软骨无变化。关节面的跟骨组织形态学也无明显变化。在临床研究中，关节镜下观察关节软骨的CO2激光照射后一年。激光照射关节软骨的颜色和柔软度没有变化

项目成果

井上和彦: 日本関節鏡学会誌. 12. 15-17 (1987)

井上和彦：日本关节镜学会杂志 12. 15-17 (1987)。

Kazuhiko Inoue: "CO2 LASER" The Journal of the Japanese Orthopaedic Association. 62. (1988)

井上和彦：“CO2 激光”日本骨科协会杂志。

Kazuhiko Inoue: "CO2 LASER Meniscectomy Under Arthroscopy" Surgery and Arthroscopy of the Knee, Eds. 1-4 (1988)

Kazuhiko Inoue：“关节镜下二氧化碳激光半月板切除术”膝关节手术和关节镜检查，编辑。

井上和彦非レーザーメスの関節鏡視手術への応用 (第1報) 非日本関節鏡学会誌: 1980. 63-66.

Kazuhiko Inoue 非激光手术刀在关节镜手术中的应用（第一次报告） 非日本关节镜学会杂志：1980。63-66。

井上和彦: 日本関節鏡学会誌. 9. 157-159 (1984)

井上和彦：日本关节镜学会杂志 9. 157-159 (1984)。