Studies on new paralytic shellfish toxin producind dinoflagellates.

麻痹性贝毒对许多国家的公众健康和渔业生产造成严重危害。本次合作研究对一种新发现的有毒甲藻链状裸甲藻（Gymatelliniumcatenatum）的生物学和产孢特性进行了研究，对该藻的生长、性行为和产孢过程进行了全面的阐述。HPLC分析表明，G.来自塔斯马尼亚的链状藻产生C1-C4毒素作为主要组分，具有少量的相当独特的十氨甲酰基毒素。在甲藻和有毒贻贝中发现一种新的毒素，经光谱分析表明为13-脱氧十氨甲酰基石房蛤毒素。本文研究了主要毒素（C1-C4）的毒性和稳定性，以及微小亚历山大藻和A.来自澳大利亚的tamarense也得到了澄清。

Paralytic shellfish poisoning causes serious hazard to both public health and fishery industries in many countries. In this collaborative study, biological and toxigenic natures of a newly found toxic dinoflagellate Gymnodinium catenatum were investigated.The growth, sexuality and cyst production of the organism were fully demonstrated. HPLC analysis indicated that G. catenatum from Tasmania produced C1-C4 toxins as major components with slight amounts of rather unique decarbamoyltoxins. A new toxin found in both dinoflagellate and toxic mussels was shown to be 13-deoxydecarbamoylsaxitoxin by spectral analysis. Toxicity and stability of major toxins (C1-C4) as well as toxin profiles of Alexandrium minutum and A. tamarense from Australia was also clarified.