Nutritional Interrelationship between Sulfate and Amino Acids in Chicks

雏鸡硫酸盐和氨基酸之间的营养相互关系

• 批准号: 63560277
• 负责人: HIKAMI Yuzo
• 金额: $ 1.02万
• 依托单位: Kobe University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63560277/
• 关键词: Sulfate; Amino acids; Methionine; Serine; Uric acid; Glutathione; Methionine activating enzyme; GOT; セリンデヒドラターゼ; タウリン; キサンチンデヒドロゲナーゼ

Feeding sulfate resulted in decreased body weight gain of chicks fed commercial formula feed containing a high content of sulfur amino acid and sulfur. On the other hand, in chicks fed a diet containing a low content of these components the body weight gain was improved by feeding sulfate.The interrelationship between sulfate and amino acids in nutrition was studied in chicks fed semi-purified diets containing soybean protein (the sole protein source) supplemented with or without 0.44% DL-methionine. The addition of sodium sulfate to the diet resulted in increased level of uric acid of blood plasma, while the content of uric acid of urine was not affected. The level of sulfur amino acids within the body was unchanged by addition of sulfate. The activity of glutamate-oxaloacetate transaminase in liver was increased by sulfate supplemented. The activity of serine dehydratase in kidney was decreased when the concentration of free serine in blood plasma was increased by addition of sulfate. The content of glutathione in liver tended to increase, and the activity of methionine activating enzyme in liver was increased markedly by addition of sulfate in chicks fed a diet containing a low level of methionine.It was shown that sulfate supplemented to the diet was utilized for synthesis of sulfur-containing compounds such as taurine, not of sulfur amino acids.

饲喂硫酸盐会导致饲喂含有高含量硫氨基酸和硫的商业配方饲料的雏鸡体重增加减少。另一方面，在饲喂这些成分含量较低的日粮的雏鸡中，饲喂硫酸盐可改善体重增加。 在饲喂含有大豆蛋白（唯一蛋白质来源）并添加或不添加 0.44% DL-蛋氨酸的半纯化日粮的雏鸡中，研究了硫酸盐与营养中氨基酸之间的相互关系。日粮中添加硫酸钠导致血浆尿酸水平升高，但尿尿酸含量不受影响。添加硫酸盐后，体内含硫氨基酸的水平没有变化。补充硫酸盐可提高肝脏谷氨酸-草酰乙酸转氨酶的活性。当添加硫酸盐增加血浆中游离丝氨酸浓度时，肾脏中丝氨酸脱水酶的活性降低。饲喂低蛋氨酸饲料的雏鸡，添加硫酸盐后，肝脏中谷胱甘肽含量呈增加趋势，肝脏中蛋氨酸激活酶活性显着提高。结果表明，饲料中添加的硫酸盐用于合成牛磺酸等含硫化合物，而不是含硫氨基酸。

项目成果

Yuzo Hikami: "The Relationship between Dietary Sulfate and the Content of SulfurーContaining Compounds and the Activity of Methionine Activating Enzyme in the Liver of Chicks" Japanese Poultry Science. 27. (1990)

Yuzo Hikami：“日粮硫酸盐与含硫化合物含量和小鸡肝脏中蛋氨酸激活酶活性的关系”《日本家禽科学》27。（1990）。

Yuzo Hikami: "The Growth Rate of Chicks fed Commercial Formula Feed Supplemented with Inorganic Sulfate" Japanese Poultry Science. 25(4). 249-253 (1988)

Yuzo Hikami：“添加无机硫酸盐的商业配合饲料喂养小鸡的生长率”日本家禽科学。

氷上雄三: "硫酸塩を添加した市販配合飼料によるヒナの成長" 日本家禽学会誌. 25. 249-253 (1988)

Yuzo Hikami：“添加硫酸盐的商业配方饲料的儿童生长”，日本家禽协会杂志 25. 249-253 (1988)。

Yuzo Hikami: "The Relationship between Dietary Sulfate and the Content of SulfurーContaining Compounds and the Activity of Methionine Activating Enzyme in the Liver of Chicks." Japanese Poultry Science. 27. (1990)

Yuzo Hikami：“日粮硫酸盐与含硫化合物的含量以及小鸡肝脏中蛋氨酸激活酶的活性之间的关系。”《日本家禽科学》27。

Yuzo Hikami: Japanese Poultry Science. 26. (1989)

Yuzo Hikami：日本家禽科学。