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Construction of Numerical Simulation System of the Left Ventricel Movement Based on the Mechanics of Myocardial Fiber

基于心肌纤维力学的左心室运动数值模拟系统的构建

基本信息

批准号：
01550072
负责人：
TOKUDA Masataka
金额：
$ 0.96万
依托单位：
Mie University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1989
资助国家：
日本
起止时间：
1989 至 1990
项目状态：
已结题

项目摘要

In the research in Heisei First fiscal year, we constructed a mechanical model of human left ventricle and the model circulation system of blood which works cooperatively with the left ventricle. Also, we can construct the numerical simulation system which can reproduce the cyclic behavior of human left ventricle, by combining the above two models. In this stage the constructed simulation system can reproduce the relation between the internal pressure and the stroke volume of blood in a reasonable accuracy. However, we used several assumptions for simplicity, in this first stage of project. For example, the left ventricle is assumed to be kept as revolutional ellipsoidal during the cyclic deformation. The assumption may be reasonable for the normal heart. But for the diseased heart, the shape may not be the revolutional ellopsoide and may change in a big variety. That is, it may be important for us to incorporate the realistic shape of left ventricle in order to estimate the local stress and the local strain for the diagonosis on the dieases on the dieases of heart. Then, in the HEISEI 2nd fiscal year, we tried to construct the system which can incorporate the realistic shape of left ventricle. The finite element numerical technique was used in two-dimensional as well as three-dimensional ways. The conclusion is that the constructed numerical simulator for the movement of left ventricle with the model of circulatory system can be used for the estimation of human left ventricle function, and it may be possible to use this system for the diagonoses on the diseased heart in some near future.

在平成第一财政年度的研究中，我们构建了人体左心室的力学模型和与左心室协同工作的血液循环系统模型。将上述两种模型结合起来，可以构建出能够再现人体左心室循环行为的数值模拟系统。在此阶段，所构建的模拟系统可以以合理的精度再现内部压力与血液的每搏输出量之间的关系。然而，为了简单起见，我们在项目的第一阶段使用了几个假设。例如，假设左心室在循环变形期间保持为旋转椭球。这一假设对于正常心脏可能是合理的。但对于病变心脏，其形状可能不是旋转椭圆形，而是变化很大。也就是说，结合左心室的实际形状来估计局部应力和应变，对于心脏疾病的诊断是很重要的。然后，在HEISEI的第二个财政年度，我们试图构建可以包含左心室的真实形状的系统。有限元数值技术被用于二维以及三维的方式。结果表明，所建立的基于循环系统模型的左心室运动数值模拟系统可用于人体左心室功能的评价，并有可能在不久的将来用于心脏病的诊断。