Valvo-Pump : Axial Blood Pump Implanted at the Heart Valve Position

瓣膜泵：植入心脏瓣膜位置的轴向血泵

• 批准号: 01870061
• 负责人: YOZU Ryohei
• 金额: $ 2.88万
• 依托单位: Keio Univ.
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B).
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01870061/
• 关键词: Valvo-Pump; Artificial Heart; Nonpulsatile blood Pump; Axial flow Pump; Nonpulsatile Flow; Heart Valve; Heart Replacement; Implantable Artificial Heart; Axial flow Pump; Non pulsatile flow; Heart valve; Implantable Antificial Heart; 人工循環; Val

The Valvo-Pump, axial nonpulsatile blood pump implanted at the heart valve position preserving the diseased heart muscle, has several advantages over artificial heart replacement. They are (a) good anatomical fitting to the natural heart, (b) less blood contacting surface, and (c) easy implantation technique as heart valve replacement. Feasibility of the concept of the Valvo-Pump was studied.The housing of the prototypical pump is a straight tube of 37 mm in diameter and 33 mm in length. Within the housing an impeller with 10 vanes is located. The impeller is connected to a samarium cobalt rare earth magnet DC brushless motor measuring 23.8 mm in diameter and 30.2 mm in length. Sealing is achieved by means of Teflon seal. A guiding wheel with four vanes is located behind the impeller.Pump was studied on a hydraulic mock circulation system to evaluate its performance characteristics. Pump flow of 5 l/min was obtained for the pump differential pressure of 90 mmHg at 4800 rpm, and 15 l/min for 70 mmHg at 4900 rpm.The Valvo-Pump will be feasible by developing a small high output power motor and an enduable seal and also by optimizing impeller design.

植入患病心肌的心脏瓣膜位置植入心脏瓣膜位置的Valvo-Pump，轴向非脉冲血泵，比人造心脏更换具有多个优势。它们是（a）对自然心脏的良好解剖结构，（b）较少的血接触表面，（c）易于植入技术作为心脏瓣膜更换。研究了Valvo-Pump的概念的可行性。原型泵的外壳是直径37毫米的直管，长度为33毫米。在房屋中，有10叶叶片的叶轮。叶轮连接到直径为23.8 mm的samarium钴稀土磁铁无刷电动机，长度为30.2毫米。密封是通过Teflon密封实现的。在叶轮后面，研究了一个带有四个叶片的引导轮。在液压模拟循环系统上研究了泵，以评估其性能特征。在4800 rpm处获得了90 mmHg的泵的差分为5 l/min的泵流量，在4900 rpm处获得70 mmHg的15 L/min，通过开发小型高输出动力电动机和一个可耐力的密封件，也可以通过优化插入器设计来可行。

项目成果

Mitamura Y, Yozu R, Tanaka T: "Valvo-Pump : Axial nonpulsatile blood pump implanted at the heart valve position." Artificial Heart. 3. (1991)

Mitamura Y、Yozu R、Tanaka T：“Valvo-Pump：植入心脏瓣膜位置的轴向非脉动血泵。”

四津 良平: "新方式,人工心臓の開発ー超小型血液ポンプの心内埋め込みー" 日本臨床. 49. (1991)

Ryohei Yotsu：“人工心脏新方法的开发——超小型血泵的心内植入”日本临床49。（1991）

Mitamura Y.,Yozu R.,Tanaka T.: "ValvoーPump:Axial nonpulsatile blood Pump implanted at the heart Valve position" Artificial Heart 3 SpringerーVerlarg. 3. (1991)

Mitamura Y.、Yozu R.、Tanaka T.：“瓣膜泵：植入心脏瓣膜位置的轴向非脉动血泵”Artificial Heart 3 Springer-Verlarg 3。 (1991)

R.Yozu,Y.Mitamura,T.Tanaka.K,Yamazaki: "Toward a Totlly Implantable Artificial Heart:Axial Nonpulsatile Blood Pump Implanted at the Heart Valve Position (ValvoーPump)" ASAIO.37. (1991)

R.Yozu、Y.Mitamura、T.Tanaka.K、Yamazaki：“走向完全植入式人工心脏：植入心脏瓣膜位置的轴向非脉动血泵（ValvoPump）”ASAIO.37。

Yoshinori Mitamura: "Valvo-Pump:Axial nonpulsatile blood pump implanted at the heart valve position" Artifical Heart 3-Springer-Verlag Tokyo. (1990)

Yoshinori Mitamura：“瓣膜泵：植入心脏瓣膜位置的轴向非脉动血泵”人工心脏 3-Springer-Verlag 东京。