Relationship between Gastrointestinal Myoelctric Activity and Portal Venous Flow before and after Truncal Vagotomy, Gastrectomy with or without Vagotomy.

禁食期间胃肠道周期性活动，胃和十二指肠有规律地出现迁移性肌电复合体（MMC），并向远端传播。喂食极大地扰乱了MMCs，然后喂食模式的均匀电活动在整个肠道中发生。空腹门静脉流量（PVF）显示轻微波动，根据胃十二指肠活动。餐后PVF的变化与肠道活动密切相关。进食后PVF很快升高，并在30min内达到平稳。PVF升高持续2小时以上，随后逐渐降至禁食值。上空肠MMC重现所需时间（MMC抑制时间）与PVF升高时间（<平均空腹PVF + 2SD）有显著相关性。截断迷走神经（TV）后，小肠周期性出现MMCs，而禁食24小时后胃中也很少出现MMCs。摄食消除了肠道中的MMCs，将禁食模式转变为摄食模式。电视后，喂食后PVF的变化呈现出多种模式。一些餐后PVF迅速增加，而另一些则非常缓慢。mmc -抑制时间和pvf -增加时间在每天和不同犬之间存在差异。电视后mmc -抑制时间与pvf增加时间无相关性。综上所述，迷走神经切断术后的运动障碍影响了肠道循环，导致肝脏门静脉血液供应紊乱。为明确胃远端部分切除术伴或不伴迷走神经切除术对肠蠕动和循环的影响，需要进一步研究肠肌电活动和PVF。

During the fasting, gastrointestinal tract showed periodic activity, and the migrating myoelectric complex (MMC) occurred regularly in the stomach and the duodenum, and propagated distally. Feeding dramatically disrupted MMCs, then uniform electrical activity of the fed pattern took place in the entire intestine.The fasting portal venous flow (PVF) showed slight fluctuation, according to the gastroduodenal activity. Postprandial changes in PVF were closely correlated with intestinal activity. After ingestion of meal, PVF soon elevated and reached plateau within 30min. Period of increased PVF persisted for more than 2 hours, then the PVF gradually decreased to the fasting value.There was significant correlation between the time required for reappearance of MMC in the upper jejunum (MMC-inhibition time) and the PVF-increasing time (<mean fasting PVF + 2SD).After truncal vagotomy (TV), periodic appearance of MMCs ws observed in the small intestine, while few MMCs occurred in the stomach even after 24-h fasting. Feeding abolished MMCs from the intestine, converting the fasting pattern to the feeding pattern.After TV, changes in PVF after feeding showed a various patterns. Some postprandial PVF increased rapidly, while another very slowly.Both MMC-inhibition time and PVF-increasing time varied in each day and between dogs. The correlation between MMC-inhibition time and PVF-increasing time was not seen after TV.In conclusion, motility disorders after vagotomy influence on intestinal circulation, causing a disturbed portal blood supply to the liver.To clarify the effects of distal partial gastrectomy with or without vagotomy on intestinal motility and circulation, Further studies on the intestinal myoelectric activity and PVF will be required.