Development of a system for measurement of bone mineral distribution patturn utilizing the dual energy subtraction technique

开发利用双能量减法技术测量骨矿物质分布模式的系统

• 批准号: 02557078
• 负责人: TSUGIHARA Katoh
• 金额: $ 8.32万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B)
• 财政年份: 1990
• 资助国家: 日本
• 起止时间: 1990 至 1992
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02557078/
• 关键词: Bone mineral content; Dual energy subtraction; Digital image process; K-edge filtration; デュアルエネルギ-差分法; デュアルエネルギ-差分; ディジタル画像処理; 希土類フィルタ

(1) Construction of the system An image processing system was constructed using a laser film scanner and a work station, communicating with Ethernet network system. The system was able to input x-ray film images 1/6 cut size with 10 bit precision within 2min. including the image data transfer to the computer.A software system previously developed on a personal computer based system, was implemented to the UNIX system. The user I/O was full GUI type constructed using Open window system, based on the Open Look standard, and most manupilation could be performed by the mous.The system could output the quantitative bone minal content data of a pixel, the profile along a line which could be arbitrally defined, the projection in a given rectangle, and the integral in a given polygon. It took about 1 hour to process the image including the image scanning, which was longer than 15min. the purposed processing time of this project. The dominat factor of the processing time was sophisticated manup … More ilating procedure based on the user's judgment.(2) Version up based on the trial use (Pacage for the indivisual application field) In order to simplify the procedure, the automatic recognition argorithm was introduced to the identification of the positions of steel ball merkers and the reference wedge. The ramp shaped reference wedge was replaced by a step wedge, which required less precission of the position. The ROI for the integration was also specifyed semi-automatically by the binarization of the target bone image. The processing time of the new version reduced to 30min. We found that the processing time reduced subatantially if an appropreate set of the predicted positions were given. We decided to develop pacages specialized to the application field, in which the shape and position of the reference wedge, film size and x-ray factors were fixed. Firstly, the gerodontic filed was chosen as the target of the prototype of the pacage, because the variation of the objects were expected to be small. We started the survay of the variation of the gerodontic objects. The pacage was expected to realize the purposed processing time within 15min. Less

(1)图像处理系统由激光胶片扫描仪和工作站组成，与以太网网络系统通信。该系统能够在2 min内输入1/6切割尺寸的X射线胶片图像，精度为10位。包括将图像数据传送到计算机，以前在基于个人计算机的系统上开发的软件系统被实现到UNIX系统。用户I/O为基于OpenLook标准的开放式窗口系统构建的全GUI型，大部分操作可由鼠标完成，系统可输出像素的定量骨密度数据、任意定义的沿着直线的轮廓、给定矩形内的投影和给定多边形内的积分。包括图像扫描在内的图像处理时间约为1小时，超过15分钟。这个项目的预定处理时间。影响加工时间的主要因素是加工工艺复杂 ...更多信息 根据用户的判断进行迭代。(2)在试用的基础上进行了改进（针对个人应用领域）为了简化程序，将自动识别算法引入到钢球梅尔克斯和基准楔块位置的识别中。斜坡形参考楔被阶梯形楔代替，阶梯形楔对位置精度要求更低。通过对目标骨图像进行二值化，半自动指定用于整合的ROI。新版本的处理时间缩短到30分钟。我们发现，如果给出一组合适的预测位置，处理时间大大减少。我们决定开发专用于该应用领域的pacages，其中参考楔的形状和位置、胶片尺寸和X射线因素是固定的。首先，选择老年牙科领域作为空间原型的目标，因为预计对象的变化很小。我们开始了老年人牙科对象的变化调查。该起搏器预期在15 min内实现预期处理时间。少

项目成果

Tsuguhisa Katoh et.al.: "Quantitative image by dual energy subtraction in a single exposure for measurement of bone mineral content" Medical & Biological Engineering & Computing. 29. 912- (1991)

Tsuguhisa Katoh 等人：“通过单次曝光中的双能量减法来测量骨矿物质含量的定量图像” 医学

加藤二久、小林賢一、水口俊介、長尾正憲: "デュアルエネルギー差分法に依る顎骨の骨塩量測定" 日本歯科補綴学会誌. 34(Suppl). 67- (1990)

Nikhisa Kato、Kenichi Kobayashi、Shunsuke Mizuguchi、Masanori Nagao：“使用双能量微分法测量颌骨中的骨矿物质含量”，日本修复医学会杂志 34（增刊）。