Development and clinical applications of digital tomosyuthesis system with the capabilities of dual energy subtraction and multi-directional tomography

双能减影多方位断层数字化断层扫描系统的研制及临床应用

• 批准号: 04404047
• 负责人: SONE Shusuke
• 金额: $ 16.64万
• 依托单位: Shinshu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (A)
• 财政年份: 1992
• 资助国家: 日本
• 起止时间: 1992 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-04404047/
• 关键词: multi-directional tomograph; digital tomosynthesis; image processing; spatial frequency filtration; dual energy subtraction; blurred mask layr subtraction; digital radiography; angiotomosynthesis; X線画像処理; 空間フィルタリング法; ボケ断層像差分法

We have developed a digital tomosynthesis system, which incorporates an x-ray fluororadiographic TV unit and has the capabilities to perform multi-directional tomography and to expose pulsed x-rays with rapid kV switching between low energy and high energy, a digital image processing unit and display unit, including a high-resolution CRT monitor and a lase printer. We have studied the methods of re-constructing digital tomographs of multilayrs, utilizing image data obtained from a single multi-directional tomographic movement, and of improving image quality of those reconstructed tomographs by means of several digital image processing techniques. The basic processing technique in our system was spatial frequency filtration, although dual energy and blurred mask layr-subtractions were the optional techniques and showed the distinct advancements shown in this study. Clinical applications of this modality has proved a number of advantages as listed below :1) Longitudinal format of the reconstructed tomographs facilitated an easy interpretation of the tomographs and helped comparison against conventional radiographs2) Digital reconstruction of multiple tomographs from a single set of tomographic image data shortened examination time and lowered patient radiation exposure. Moreover it helped three-dimensional recognition of the object when multiple tomographs were displayd on a CRT in cine mode3) Image processing was effective to improve image quality of the tomograph and enhanced some specific image informations pertinent to the clinical problem at hand4) Dual energy subtraction digital tomosynthesis was effective to clearly demonstrate bony structures or a small calcification in the lesion and permitted discrimination of calcifications from dense fibrotic lesions5) Digital angiotomosynthesis permitted a detailed observation of vascular disorders and was promising for dynamic vascular study

我们已经开发了一个数字断层合成系统，它包括一个X射线荧光造影电视单元，并具有执行多方向断层扫描和曝光脉冲X射线与低能量和高能量之间的快速kV切换的能力，一个数字图像处理单元和显示单元，包括一个高分辨率CRT显示器和一个激光打印机。我们研究了利用从一个单一的多方向层析运动获得的图像数据重建多层数字层析图像的方法，以及通过几种数字图像处理技术来改善这些重建的层析图像的图像质量的方法。在我们的系统中的基本处理技术是空间频率滤波，虽然双能量和模糊掩模层减法是可选的技术，并显示在这项研究中所示的显着进步。该模式的临床应用已证明具有以下优点：1）重建断层照片的纵向格式便于轻松解释断层照片，并有助于与传统X射线照片进行比较2）从单组断层图像数据中数字重建多个断层照片缩短了检查时间并降低了患者辐射暴露。此外，当在电影模式下在CRT上显示多个断层图像时，它有助于物体的三维识别3）图像处理有效地提高了断层图像的图像质量，并增强了与手头临床问题相关的某些特定图像信息4）双能量减影数字断层合成摄影可有效地清晰显示病变中的骨性结构或小钙化，并可区分致密纤维化病变的钙化5）数字化血管断层合成术可以详细观察血管疾病，并有望用于动态血管研究

项目成果

Sone, Shusuke, et al: "Chest imaging with dual-energy subtraction digital tomosynthesis" Acta Radiol. 34. 346-349 (1993)

Sone、Shusuke 等人：“双能减影数字断层合成胸部成像”Acta Radiol。

Shusuke Sone,et al: "Estensione della patologia mediastinica quale appare neiradiogrammi tradizionali:Correlazione con le immagini assiali trasverse" R.Bergonzini,et al Brescia,Italy, 5 (1992)

Shusuke Sone 等人：“Estensione della patologia mediastinica quale appare neiradiogrammi tradizionali：Correlazione con le immagini assiali trasverse” R.Bergonzini 等人 Brescia，意大利，5 (1992)

春日 敏夫: "ディジタルラジオグラフィ -I.I.-TV系のDR-" 映像情報. 23. 196-200 (1991)

Toshio Kasuga：“数字放射线摄影 -I.I.-TV 系统 DR-”视频信息。23. 196-200 (1991)

Shigeta Hiroaki: "Digital angiotomosynthesis for preoperative evaluation of cerebral arteriovenous malformations and giant aneurysms" AJNR. 15(in Press). (1994)

Shigeta Hiroaki：“数字血管断层合成术用于脑动静脉畸形和巨大动脉瘤的术前评估”AJNR。

Sone Shusuke: "Sviluppo ed applicazione clinica della tomosintesi TV digitale e a raggi X e di uno sviluppo di immagine con FCR" R Bergonzini,GM Favagraossa,D Malavasi, 7 (1992)

曾根周介：“Sviluppo ed applicazione Clinica della tomosintesi TV digitale e a raggi X e di uno sviluppo di immagine con FCR”R Bergonzini、GM Favagraossa、D Malavasi，7 (1992)