Development and application of automatic analyzer for sensitive catalytic analysis

灵敏催化分析自动分析仪的研制与应用

• 批准号: 02650538
• 负责人: FUKASAWA Tsutomu
• 金额: $ 1.15万
• 依托单位: Yamanashi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1990
• 资助国家: 日本
• 起止时间: 1990 至 1991
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02650538/
• 关键词: Catalytic analysis; automation of analysis; determination of iodide ion

A flow system with air carrier was developed as a new automatic analyzer for sensitive catalytic analysis. The analyzer was applied to determine iodide ion by measurement of a coloration rate constant of a new redox reaction using iodide-catalyzed oxidation of Chlorpromazine (CP) with H_2O_2 in H_2SO_4 (the pseudo zero-order reaction).(1) The analyzer consists of injectors and a laboratory-made micro cell, which are connected in series by PTFE tubing with 1 and 2 mm i. d. Each 150 mul of sample and two reagent solutions were introduced into the flow system by pumping and siphoning. The precision of siphon injection was 0.2%, comparable to a manual syringe injection. The three air-segmented solution zones were carried by air pumping, into the cell, in which the solutions were mixed to initiate a reaction and measure the reaction rate constant. Reproducible mixing was performed within an error of 1% in absorbance measurement of rfethyl Orange solution mixed with water and CP solution.(2) By a manual batch technique, the reaction condition of reactant concentrations and reaction temperature were optimized for sensitive determination of iodide ion.(3) The detection limit of iodide ion using the analyzer was 3 ng, which was lower than that of about 50 ng by the batch technique.

本文介绍了一种新型的空气载流系统，用于灵敏催化分析。用该仪器测定了在H2SO4介质中碘催化H2O2氧化氯丙嗪（CP）的新氧化还原反应（准零级反应）的显色速率常数，从而测定了碘离子。(1)该分析仪由注射器和实验室自制的微池组成，它们通过直径为1和2 mm的PTFE管串联。D.通过泵送和虹吸将每150穆尔样品和两种试剂溶液引入流动系统。虹吸进样的精密度为0.2%，与手动注射器进样相当。通过空气泵送将三个空气分段的溶液区带入池中，在池中混合溶液以引发反应并测量反应速率常数。在与水和CP溶液混合的rfethyl橙子溶液的吸光度测量中，进行了可重现的混合，误差为1%。(2)采用手动间歇法，对碘离子的反应物浓度和反应温度进行了优化。(3)碘离子的检出限为3 ng，低于批处理法的50 ng。

项目成果

Tsutomu Fukasawa, Liang Bing.: ""Catalytic determination of iodide using chlorpromazine - hydrogen peroxide redox reaction"" Bunseki kagaku. (1992)

深泽勉、梁冰：“氯丙嗪-过氧化氢氧化还原反应催化测定碘化物”文石化学。

深沢 力: "空気をキャリヤ-とする流れ分析法を用いた極微量ヨウ化物イオンの接触定量" 分析化学. (1992)

Tsutomu Fukazawa：“使用空气作为载体的流动分析催化测定痕量碘离子”《分析化学》（1992 年）。