Comprehensive study on food intake
Comprehensive study on food intake
批准号:
03304042
负责人:
SATO Toshihide
金额:
$12.86万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Co-operative Research (A)
财政年份:
1991
资助国家:
日本
项目状态:
已结题
起止时间:
1991 至 1993
中文摘要
1. 存在于味觉细胞接受膜和基底膜上的多种离子通道在味觉转导中起着重要的作用,杏仁核和皮层味觉区与睾丸刺激的识别、识别和记忆有关。梅克尔细胞的诱导能力使舌头上的睾丸芽得以发育。明确了口腔体感信息投射到臂旁核的中间水平,部分髓神经信号投射到三叉神经的中脑核。大鼠在识别味觉质量后的实际进食行为与从脑桥睾丸区投射的下丘脑神经元和从脑桥、丘脑和大脑皮层的味觉区投射的杏仁核神经元有关。唾液分泌的特征随食物的变化而变化,这与延髓内唾液区神经元的冲动模式相对应。4 .猫颅喉核的部分神经元从三叉神经脊髓束核内插亚核的尾状和喙状核上投射出来。结果表明,这些存在于唇部、上颚和面部的副交感神经血管舒张反射与月食摄入和咀嚼运动有关。在脑干和皮层形成的咀嚼节奏最终通过整合控制,在皮层的体感区,来自舌头口腔黏膜、牙周韧带、牙龈、嘴唇和脸颊等的感觉传入信号在进食和咀嚼运动的情况下没有出现。未麻醉的家兔在上、下牙间挤压坚硬的食物,闭合后期的下颚运动速度暂时降低。相应的现象是咬肌肌电图出现一过性抑制,二腹肌肌电图出现一过性活动。这是由于牙周韧带对咀嚼的反射控制,牙周-咀嚼反射对咀嚼运动的控制通过大尺寸的运动单元更有效地完成。少
英文摘要
1. A variety of ion channels existing in the receptive and basolateral membrances of taste cells play an important role in gustatory transductionl Amygdala and cortical taste area are concerned with identification, recognitiona and memory of teste stimuli. The ability of induction of Merkel cells makes the development of teste buds in the tongue.2. It was clarified that oral somatosensory information projects to the intermediate level of the parabrachial nucleus and that a part of pulpal nerve signals projects to the mesencephalic nucleus of the trigeminal nerve.3. Actual food intake behavior in rat after recognition of the taste quality is concerned with the hypothalamus neurons projected from the pontine teste area and the amygdala neurons projected from the taste areas of the pons, thalamus and cortex.4. The aspects of a secretion of salva change with a kind of foods, and this corresponds to impulse pattern of neurons in the salivary unclei of the medulla oblongate. Some neurons in … More the cranial salvary nucleus in cat are projected from the caudal and rostal unclei within the subnucleus interpolaris of the spinal tract nuclei of the trigeminal nerve.5. It was clarified that these exist parasympathetic vasodilatation reflexes in the lip, palate and face which are involved in the intake of foods into the month and the chewing movement.6. Chewing rhythm which is formed in the brain stem and cortex is finaly controlled by integrating, in the somatosensory area of the corgtex, sensory afferent signals from oral mucosa of the tongue, periodontal ligament, gingiva, lip and cheek, etc. did not appear in case of food intake and chewing movement.7. What an unanesthetized rabbit crushed a hard food between upper and lower denitions, the velocity of jaw movement at the late closing phase was temporarily lowered. As the corresponding pheonomenon, a transient inhibitionof masseter muscle EMG and a trasient activity of digastric muscle EMG appeared. This is due to the reflex control of mastication by the periodontal ligament Control of masticatory movement by the periodontal-massetric reflex is more effectively done gy a large size of the motor units. Less
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Toyoshima,K.: "Are Merkel and Grandry cells two varieties of the same cell?" Arch.Histol.Cytol.56. 262 (1993)
Toyoshima,K.:“默克尔细胞和格兰德里细胞是同一细胞的两种变体吗?”
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通讯作者:
Hayashi, H., et al.: "Distribution of trigeminal sensory nucleus neurons projection to the mesencephalic parabranchial area of the cat" Neurosci. Lett.122. 75-78 (1991)
Hayashi, H. 等人:“三叉神经感觉核神经元投射到猫的中脑旁臂区域的分布”Neurosci。
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Katayama, T., et al.: "Control of trigeminal motoneurons from the cerebellar interpositus nucleus of the guinea pig" J.Neurophysiol. 1528-1542 (1992)
Katayama,T.,等人:“豚鼠小脑间核对三叉神经运动神经元的控制”J.Neurophysiol。
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Hayashi, H., et al.: "Bulbar reticular neurons relaying somatosensory information to the messencephalic parabranchial area of the cat" Brain Res.574. 329-332 (1992)
Hayashi, H. 等人:“球网状神经元将体感信息传递到猫的中脑旁臂区域”Brain Res.574。
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Haraguchim, N., et al.: "Short electromyographic bursts in the rabbit diagastric muscle during jaw closing phase" Arch. Oral Biol.37. 451-458 (1992)
Haraguchim, N. 等人:“在下颌闭合阶段,兔子双腹肌出现短暂的肌电图爆发”Arch。
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共 109 条
Molecular mechanisms of ion channels and second messengers in gustatory transduction of taste cells.
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批准号:08457491
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.48万
-
财政年份:1996
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负责人:SATO Toshihide
-
依托单位:
Development of system for analyzing membrane proteins of taste cells ender physiological condition.
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批准号:07557117
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$7.68万
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财政年份:1995
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负责人:SATO Toshihide
-
依托单位:
Molecular mechanisms of transduction of gustatory stimuli in human and mammalian tatse cells.
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批准号:05404063
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项目类别:Grant-in-Aid for General Scientific Research (A)
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资助金额:$11.9万
-
财政年份:1993
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负责人:SATO Toshihide
-
依托单位:
Distribution, isolation and reconstitution of functional molecules related to the taste-signal transduction.
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批准号:04557080
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$5.89万
-
财政年份:1992
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负责人:SATO Toshihide
-
依托单位:
Molecular mechanism of gustatory transduction in taste cells
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批准号:01480433
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.97万
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财政年份:1989
-
负责人:SATO Toshihide
-
依托单位:
Transduction mechanism of four basic taste stimuli into electric signals of taste cell
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批准号:60480402
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.16万
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财政年份:1985
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负责人:SATO Toshihide
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依托单位:
海外基金