Silent otitis media and eustachian tube function in individuals with head and neck tumor

头颈肿瘤患者的无声性中耳炎和咽鼓管功能

• 批准号: 03670823
• 负责人: YAMAGUCHI Nobumasa
• 金额: $ 1.28万
• 依托单位: The Jikei University School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1991
• 资助国家: 日本
• 起止时间: 1991 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03670823/
• 关键词: silent otitis media; head and neck tumor; eustachian tube function; impedance method; sonotubometry; patulous eustachian tube; 頭頚部悪性腫瘍; impedance法; 客観的耳管機能

In histopathological studies, silent otitis media in autopsy cases with advanced malignant tumors of the head and neck had been reported. In this clinical study, silent otitis media was detected in cases with head and neck tumors and, furthermore, patulous eustachian tube was proved to be related to head and neck tumors. The otitis media in head and neck tumors was caused by tumor, irradiation, and surgical therapy. Hitherto, otitis media was considered to be related to stenosis of the eustachian tube, however patulous eustachian tube poses a possibility of causing silent otitis media. Patulous eustachian tube was detected by endoscopic findings of the tympanic membrane and the pharyngeal orifice through video monitor observation, the impedance method, and sonotubometry. Patulous eustachian tube in head and neck tumors was probably due to atrophy of the lymphoid tissue and glands aroud the eustachian tube resulting from radiotherapy and/or one of the causative factors of the loss of weight in aged male patients.

在组织病理学研究中，已有报道在头颈部晚期恶性肿瘤尸检病例中发现无症状中耳炎。在临床研究中，在头颈部肿瘤患者中发现了隐匿性中耳炎，并进一步证实咽鼓管扩张与头颈部肿瘤有关。头颈部肿瘤中耳炎是由肿瘤、放疗和手术治疗引起的。到目前为止，中耳炎被认为与咽鼓管狭窄有关，然而咽鼓管扩张有可能导致静止性中耳炎。通过视频监护观察、阻抗法、声管测定仪对鼓膜和咽口进行内窥镜检查，发现咽鼓管未闭。头颈部肿瘤的咽鼓管畸形可能是由于放疗引起咽鼓管周围淋巴组织和腺体萎缩和/或老年男性患者体重减轻的原因之一。

项目成果

山口 展正: "インピーダンスオージオメトリーによる耳管機能検査" Johns. 8. 763-768 (1992)

Nobumasa Yamaguchi：“使用阻抗测听法测试咽鼓管功能”Johns。8. 763-768 (1992)

Nobumasa Yamaguchi et al: "Patulous Eustachian tube:Endoscopic of the tympanic membrane and the pharyngeal orifice of the Eustachian tube and the impedance method," Proceedings of International Symposium on Recent Advances in Otitis Media.Kugler. (in pres

Nobumasa Yamaguchi 等人：“咽鼓管扩张：鼓膜和咽鼓管咽口内窥镜检查和阻抗法”，《中耳炎最新进展国际研讨会论文集》。Kugler。

Nobumasa Yamaguchi et al: "Patulous Eustachian tube:Endoscopic of the tympanic membrane and the pharyngeal orifice of the Eustachian tube and the impedance method" Proceedings of International Symposium on Recent Advances in Otitis Media.Kugler. (in press

Nobumasa Yamaguchi 等人：“咽鼓管扩张：鼓膜和咽鼓管咽口内窥镜检查及阻抗法”中耳炎最新进展国际研讨会论文集。Kugler。

Yamaguchi, Nobumasa et al: "Eustachian tube function by impedance method" Johns. 8. 763-768 (1992)

Yamaguchi、Nobumasa 等人：“通过阻抗法测量咽鼓管功能”Johns。

Yamaguchi, Nobumasa et al: "The Eustachian tube function and prognosis of OME after removal of the ventilatory tube." Recent advances in otitis madia Decker Decker Pacicals. 95-95 (1993)

Yamaguchi、Nobumasa 等人：“摘除通气管后 OME 的咽鼓管功能和预后”。