Semiconductor Catalyzed Addition Reactions Driven by Visible Light

可见光驱动的半导体催化加成反应

• 批准号: 5247606
• 负责人: Professor Dr. Horst Kisch
• 金额: --
• 依托单位: Lehrstuhl für Anorganische und Allgemeine Chemie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2000
• 资助国家: 德国
• 起止时间: 1999-12-31 至 2003-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5247606?language=en
• 关键词: Semiconductor; Catalyzed; Addition; Reactions; Driven

Aim of this project is to develop solar syntheses of fine chemicals having potential biological activity. This shall be accomplished through visible light-driven addition reactions between unsaturated substrates catalyzed by semiconductor powders. Addition reactions in generally are environmental friendly processes since they do not produce useless by-products. As recently discovered in the laboratory of the german group, cadmium sulfide powders photocatalyze the addition of olefins to imines affording hitherto unknown homoallyl amines. In the case of an imino ester the product is an unsaturated a-amino acid ester, which can be easily converted into the corresponding a-imino acid. According to the first mechanistic investigations the semiconductor photocatalyzes a proton-coupled double electron transfer between donor and acceptor substrates. This unconventional heterogeneous photosensitization mechanism opens a wide field in solar syntheses of fine chemicals. Before this can be successfully explored, some basic mechanistic knowledge has to be gained. This work shall be performed in Erlangen due to the experience of this group in semiconductor photocatalysis. Since the Izmir group has already conducted solar chemical reactions, the solar synthesis of the amino acid esters will be executed there.

该项目的目的是开发具有潜在生物学活性的精细化学物质的太阳能合成。这应通过通过半导体粉末催化的不饱和底物之间的可见光驱动反应来实现。通常，加法反应是环保过程，因为它们不会产生无用的副产品。正如最近在德国集团实验室发现的那样，硫化镉会在迄今为止迄今未知的同胺胺上添加烯烃的烯烃。在伊米诺酯的情况下，产物是一种不饱和的A-氨基酸酯，可以轻松地转换为相应的A-氨基酸。根据第一个机械研究，半导体光催化在供体和受体底物之间质子偶联的双电子转移。这种非常规的非均质光敏机制在精细化学物质的太阳能合成中开辟了广泛的领域。在可以成功探索此之前，必须获得一些基本的机械知识。由于该组在半导体光催化中的经验，应在Erlangen中进行这项工作。由于IZMIR组已经进行了太阳化学反应，因此将在此处执行氨基酸酯的太阳能合成。