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Development and Practicability of Flame Sprayd Apatite Coated Titanium Implant System

火焰喷涂磷灰石涂层钛种植体系统的研制与实用化

基本信息

批准号：
03557088
负责人：
MICHI Ken-ichi
金额：
$ 8.26万
依托单位：
Showa University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Developmental Scientific Research (B)
财政年份：
1991
资助国家：
日本
起止时间：
1991 至 1993
项目状态：
已结题

项目摘要

We have been using sintered hydroxylapatite (HA) dental implants and plasmasprayd HA coated implants. Desirable properties of the former type include thinner HA layr and ability to provide structures for mechanical retention, properties of the latter are stronger adhesion to the titanium surface, better retention and more stable apatite structures. We have now developed a flame sprayd apatite coated titanium(AFC) implant in an effort to improve some of these properties. The results of the experimental study of AFC implant may be summarized as follows. (1)This implant showed good osteointegration. (2)Little imflammatory change was observed in the surrounding soft tissue. (3)Mononuclear or multinuclear cells wereoberved in contact with HA surface. Although there was elution of HA grains fromlimited areas, no obvious resorption was observed on the HA surface. These findings suggest possible clinical applications of this system.Based on the histology, we have developed a System of AFC Implants. AFC implants were installed between October 1991 and January 1993 in 24 patients. Application of our dental implants made well retained and stable implant prostheses for these patients. Our dental implants are available for, not only edentulous patients, but also for patients who require prostheses and for whom functional restoration is difficult by conventional prosthodontic methods.

我们一直在使用烧结羟基磷灰石（HA）牙科种植体和等离子喷涂HA涂层种植体。前一种类型的理想性能包括更薄的HA层和提供用于机械保持的结构的能力，后一种类型的性能是对钛表面更强的粘附性、更好的保持性和更稳定的磷灰石结构。我们现在已经开发了一种火焰喷涂磷灰石涂层钛（AFC）植入物，以改善这些性能。AFC植入物的实验研究结果总结如下。（1）该种植体表现出良好的骨结合。（2）周围软组织无明显炎性改变。（3）在HA表面可观察到单核或多核细胞。HA颗粒在局部区域有洗脱现象，但表面无明显吸收。这些结果表明，该系统可能的临床应用。根据组织学，我们已经开发了AFC植入系统。1991年10月至1993年1月期间，在24名患者中安装了AFC植入物。我们的种植体的应用使这些患者获得了良好的固位和稳定的种植修复。我们的牙科种植体不仅适用于缺牙患者，还适用于需要修复的患者以及传统修复方法难以恢复功能的患者。