Micro-electrofluidic platforms for monitoring 3D human biological models

用于监测 3D 人体生物模型的微电流体平台

• 批准号: DP220102872
• 负责人: Prof Brett Paull
• 金额: $ 36.05万
• 依托单位: University of Tasmania
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-06-28 至 2025-06-27
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP220102872
• 关键词: Micro; electrofluidic; platforms; monitoring; 3D

The ability to study living cells and human biological models (cell cultures) delivers greater understanding of basic biological function and response to applied (bio)chemical stimuli. Creating the physical environments to sustain biological models, and mimic natural conditions and fluidic pathways, is immensely challenging, yet essential to deliver meaningful observational data. This project will deliver this capability through the convergence of expertise and innovation in analytical chemistry, materials science and cellular biology, ultilising the latest technology and understanding of 3D micro/electrofluidics, to enable the study and stimulation of advanced biological models, sustained within precisely controlled 3D micro-environments.

研究活细胞和人类生物模型（细胞培养物）的能力提供了对基本生物功能和对应用（生物）化学刺激的反应的更好理解。创建物理环境来维持生物模型，并模拟自然条件和流体路径，是非常具有挑战性的，但对于提供有意义的观测数据至关重要。该项目将通过融合分析化学、材料科学和细胞生物学方面的专业知识和创新，利用最新技术和对3D微/电流体的理解，实现对先进生物模型的研究和刺激，并在精确控制的3D微环境中持续进行。