Integlation of Sensory Motor Functions in the Oral facial Maxillal Areas

口腔面部上颌区域感觉运动功能的整合

• 批准号: 07307017
• 负责人: HAYASHI Haruhide
• 金额: $ 12.99万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07307017/
• 关键词: Integration of sensory; Function of Oro-Maxillo-Facial Region Motor Function; Oral Sensation; Gustatory Sensation; Mastication; Salival secretion; Periodontal Membrane; 歯根膜; 運動・感覚の統合機構; 感覚・運動の統合機構

In 1995 and 1996, the input and output, and inside neural circuitry and their properties were identified and investigated in the various levels of neural systems contributing sensory-motor functions in the oral-facilal-maxillal areas. In this final year, integrative functions in each level were analyzed and speculated based on the results obtained in the previous years, as follows.(1) Interactions and integration of the ionic channels and intracellular transmission mechanisms in the frog taste receptor cell and membrane for various taste stimuli.(2) Integration of taste responses in the primary taste afferents to quinine-HCl and amino acids.(3) Integration of neural information in the amygdala and cortical gustatory area during the conditioned taste aversion.(4) Integration of somatic and motor information in the the sensory trigeminal nucleus based on the EM-observation of neural architechture.(5) Integration of pain and somatic sensation in the awake monkey cortex.(6) Integration of the masticatory rhythm generation during NMDA-induced rhythmic activities in the in vitro brainstem preparations.(7) Integration of periodontal and muscle spindle information in the brainstem in the anesthetized and awake animals.(8) Development of the masticatory robots and reserches on the integration of masticatory movement using it.

1995年和1996年，在口腔-设施-上颌区参与感觉-运动功能的不同层次的神经系统中，对输入和输出、内部神经回路及其特性进行了识别和研究。在最后一年，根据往年的结果，对各个层次的综合功能进行了分析和推测，具体如下：(1)蛙味觉受体细胞和膜中离子通道的相互作用和整合以及细胞内传递机制对各种味觉刺激的影响。(2)初级味觉传入对奎宁-盐酸和氨基酸的味觉反应整合。(3)条件性味觉厌恶过程中杏仁核和皮层味觉区神经信息的整合。(4)基于神经结构的电成像观察，三叉神经感觉核中躯体和运动信息的整合。(5)清醒猴皮层疼痛和躯体感觉的整合。(6)在体外脑干制剂中nmda诱导的节律活动中咀嚼节律产生的整合。(7)麻醉和清醒动物脑干牙周和肌纺锤体信息的整合。(8)咀嚼机器人的研制及其咀嚼运动集成研究。

项目成果

Uchida,Y.: "Changes in outward K^+ currents in response to two types of sweeteners in sweet taste transduction of gerbil taste cells." Chem.Senses,. 22,1. 163-169 (997)

Uchida,Y.：“在沙鼠味觉细胞的甜味转导中，外向 K^ 电流的变化响应两种类型的甜味剂。”

Shimura, T.: "Salient responsiveness of parabrachial neurons to the conditioned simulus after the acquisition of taste aversionlearing in rats." Neuroscience. 81,. 239-247. (1997)

Shimura, T.：“大鼠获得味觉厌恶后，臂旁神经元对条件模拟的显着反应。”

Hidaka,O.: " Regulation of masticatory force during cortically induced rhythmic jaw movements in the anesthetized rabbit." J.Neurophysiol.77. 3168-3179 (1997)

Hidaka,O.：“麻醉兔子皮质诱导的有节奏的下颌运动期间咀嚼力的调节。”

Tsumori, T.: "Organization of the nigro-bullbar pathway to the parvicellular reticular fromation:a light-and electron-microscopic study in the rat." Experimental Brain Research. 116:. 341-350 (1997)

Tsumori, T.：“小细胞网状结构的黑牛棒通路的组织：大鼠的光和电子显微镜研究。”

Yashiro, K.: "Tongue, jaw and lip muscle activity and jw movement during chewingefforts in man" Dent.Res.75 (8). 1598-1606 (1996)

Yashiro, K.：“人类咀嚼过程中舌头、下巴和嘴唇的肌肉活动和 jw 运动”Dent.Res.75 (8)。