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Trial Projection of High Speed Optical Computed-Tomograph using Large Transmitted Light Image

使用大透射光图像的高速光学计算机断层扫描的试验投影

基本信息

批准号：
07558253
负责人：
UMEDA Tokuo
金额：
$ 3.33万
依托单位：
Hiroshima Prefectural College of Health and Welfare
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1996
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07558253/
关键词：
Optical CT Generation of Degital Medical Image Uninvation Tomography Device リアルタイム光CT 平面透過光像画像再構成無侵襲光CT 断層像

项目摘要

Optical computed tomography (Optical CT) has been expected to offer specific diagnostics information on the physiological activities and defects. However, the strong diffusion of light in biological tissues hinders the detection of projection data, i. e. the intensity of light is integrated along straight lines, which is necessary for the CT image reconstruction algorithm currently used for x-ray CT.Several methods have been proposed to detect quasi-straightforward-propagating (QSP) photons of the biological tissue. In our previous research, we investigated the method using light polarization to extract light components traveling along a nearly straight line in a diffused medium.A method utilizing light polarization was applied to take the projection data of absorbers in a highly scattering medium. The floor level of the projection data due to diffused light was significantly suppressed by detection of photons which preserved initial polarization. An optical CT image was reconstructed from the projection data taken by this method and exhibited higher special resolution than the image reconstructed from the projection data by conventional method.In summary, it was confirmed that the contrast of projection data for the optical CT was improved by the detection of transmitted light component which preserved the initial polarization as a result of suppression of the diffused light. The optical CT image of two absorbers in the test scattering medium (1.2% aqueous solution of "Intralipid 10%") 75mm thick was reconstructed from the projection data measured by the method using a phase-modulator. The two absorbers were clearly separated in the CT image, but were not separated in that reconstructed from the total transmitted intensity.

光学计算机断层扫描（光学CT）已被期望提供特定的诊断信息的生理活动和缺陷。然而，光在生物组织中的强漫射阻碍了投影数据的检测，即。e.光的强度沿沿着直线积分，这对于当前用于X射线CT的CT图像重建算法是必需的。已经提出了几种方法来检测生物组织的准直接传播（QSP）光子。在我们之前的研究中，我们研究了利用光偏振来提取漫射介质中沿着近直线传播的光分量的方法，并采用利用光偏振的方法来获取高散射介质中吸收体的投影数据。由于漫射光导致的投影数据的最低水平被保留初始偏振的光子的检测显著抑制。从用该方法得到的投影数据重建的光学CT图像显示出比用常规方法从投影数据重建的图像更高的空间分辨率，总之，确认了通过检测透射光分量改善了光学CT的投影数据的对比度，该透射光分量由于抑制了漫射光而保持了初始偏振。用相位调制器从该方法测得的投影数据中重建了两个吸收体在75mm厚的测试散射介质（1.2%的“Intralid10%”水溶液）中的光学CT图像。两个吸收体在CT图像中被清楚地分离，但在从总透射强度重建的图像中没有分离。