STUDY OF EFFECT OF SENSORY INPUT TO VOLUNTARY MOVEMENT MEASURED BY MAGNETOENCEPHALOGRAPHY

通过脑磁图测量感觉输入对自主运动的影响的研究

基本信息

批准号：
07670711
负责人：
NAGAMINE Takashi
金额：
$ 1.41万
依托单位：
KYOTO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1996
项目状态：
已结题

项目摘要

Effect of sensory input to voluntary movement has been studied by magnetoencephalography (MEG).(1) Stable recording of somatosensory evoked magnetic field (SEF)In order to avoid stimulus artifact produced by the short duration electric shock, various kinds of grounding have been tried. Placement of wide grounding electrode around the forearm proximal to the stimulus electrode revealed the complete elimination of the artifact.(2) Recovery function of SEFPaired electric shock with various interstimulus interval (ISI) ranging from 10 to 200 ms was applied to the median nerve and SEF was recorded. Subtraction of SEF to single shock from that to the paired shock resulted in the net response to the second shock. ISI with 20-60 ms produced suppression on the component 40-60 ms after the stimulus. Other components seemed to be stable.(3) Movement-related magnetic field (MRCF)Since MEG equivalent (Readiness field, RF) to Bereitschaftspotential (BP) starts later than BP in selfpaced movement, interval for self-pace movement has been evaluated, which does not interfere the RF.Interval exceeding 1.5 s disclosed that response can be recognized as that corresponding to a single movement.(4) Interference to SEF by movementRandom button press with approximately 3 s interval was requested to normal volunteers, during the session with random electric shock with intervals ranging from 0.9 to 1.3s. SEF was categorized with respect to the timing to the voluntary contraction. Although SEF became smaller when the button press preceded the electric shock within 900 ms, SEF was not affected by the following voluntary movement even if it occurred within 900 ms after the electric shock.These results indicate the close relationship between the sensory and motor cortex.

感觉输入对自愿运动的影响已经通过磁脑电图（MEG）研究。（1）为了避免短持续时间电击产生的刺激性伪影，稳定记录了体感诱发的磁场（SEF），尝试了各种接地。在刺激电极附近的前臂近端周围放置宽接地电极，显示了伪影的完全消除。（2）将隔离电击的恢复函数恢复了范围为10至200 ms的各种间隔间隔（ISI）的恢复功能，并记录了中间神经并记录了SEF。 SEF对单个冲击的减去对配对的冲击导致对第二次冲击的净响应。刺激后40-60毫秒对成分产生20-60 ms的ISI。（3）与动作相关的磁场（MRCF），因为MEG等效（准备场，RF）与Bereitschaftspotitials（BP）的开始晚于BP在自动运动运动中的时间晚，因此已经评估了自节度运动的间隔，并且无法识别1.5 s eversyve sef sefterval sefference sefterval seforce sef。通过Movemrandom按钮按大约3 s间隔的按钮向普通志愿者要求，在会话中，随机电击，间隔为0.9至1.3。 SEF根据自愿收缩的时间分类。尽管当按钮在900毫秒内进行电击之前，SEF变小，但即使在电击之后900毫秒内发生，SEF也不会受到以下自愿运动的影响。这些结果表明感觉和运动皮层之间的密切关系。