Developmental change of hemispheric dominance using visual event-related potentials (ERPs)

使用视觉事件相关电位（ERP）观察半球优势的发育变化

• 批准号: 07670875
• 负责人: KAMIMURA Naohisa
• 金额: $ 0.96万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07670875/
• 关键词: Event-related potential; P300; Hemispheric dominance; Visual recognition; verbal stimulation; non-verbal stimulation; 事象関連電位; 反応時間; 視覚認知

In order to determine the dominant hemisphere of visual recognition and examine the developmental changes of the hemispheric dominance, event-related potentials (ERPs) were recorded in 20 normal adlescence (21-45 years of age) and 40 normal children (6-12 years of age). Visual stimuli of verbal ("Kana") and non-verbal ("Dot" in space and "Face") were presented using a tachistoscope and "oddball" paradigm.In normal adlescence (right handers), the P300 amplitude in verbal stimulation to right-visual field were higher than those to left-visual field. On the other hand, the P300 amplitude in non-verbal stimulation to left-visual field were higher than those to right-visual field. These findings suggest that P300 to the tachistoscopic visual stimuli could determine the hemispheric dominance. In normal right-handed adlescence, dominant hemisphere of verbal recognition present in the left and that of nonverbal recognition in the right.In normal right-handed children elder than 6 years of age, the P300 amplitude in verbal stimulation to right-visual field were also higher than those to left-visual field. The P300 amplitude in non-verbal stimulation "Dot" to left-visual field were higher than those to right-visual field in the children elder than 8 years of age. These findings suggest that hemispheric dominance of verbal recognition had already presented in the left in the children elder than 6 years of age and that of non-verbal recognition presented in the right in the children elder than 8 years of age.Further study in the children younger than 6 years of age would give the precise observation of the developmental change of hemispheric dominance of visual recognition.

为了确定视觉识别的优势半球并检查优势半球的发育变化，记录了20名正常青少年（21-45岁）和40名正常儿童（6-12岁）的事件相关电位（ERP）。使用视速镜和“oddball”范式呈现言语（“假名”）和非言语（空间中的“点”和“脸”）的视觉刺激。在正常青春期（右撇子）中，言语刺激对右视野的 P300 幅度高于对左视野的言语刺激。另一方面，非语言刺激对左视野的P300幅度高于对右视野的P300幅度。这些发现表明 P300 对速视视觉刺激可以确定半球优势。正常右手青少年，语言识别优势半球位于左侧，非语言识别优势半球位于右侧。6岁以上正常右手儿童，言语刺激对右视野的P300幅度也高于对左视野的刺激。 8岁以上儿童非言语刺激“点”对左视野的P300幅度高于对右视野的P300幅度。这些结果表明，6岁以上儿童的言语识别优势半球已呈现在左侧，8岁以上儿童的非言语认知优势已呈现在右侧。通过对6岁以下儿童的进一步研究，可以更精确地观察视觉认知优势半球的发育变化。