Prospective study of Detachable coil embolization for PDA

可拆卸弹簧圈栓塞治疗PDA的前瞻性研究

• 批准号: 07670896
• 负责人: INO Toshihiro
• 金额: $ 0.96万
• 依托单位: Juntendo University School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07670896/
• 关键词: coil embolization; Detachable coil; patent ductua arteriosus; 動脈管開存症; detachable system; カラードプラー

Background. Coil embolization has recently been used as an effective alternative to surgery in treating patent ductus arteriosus. This report presents the results of coil occlusion of patent ductus arteriosus using detachable and non-detachable embolization systems with modified long Gianturco coils having more than 5 helical loops. Furthermore, it provides an intermediate-term natural history of coils implanted in the ductus.Methods and Results. Twenty-two patients, ranging in age from 2 years and 9 months to 12 years and 10 months (mean(]SY+-[)SD : 6.5(]SY+-[)3.6 years), underwent coil occlusion. The ductus ranged from 1.0 to 3.5mm (mean2.6(]SY+-[)0.7mm) in diameter at the narrowest point. In 11 of these patients regular coils were implanted using the non-detachable system, while in the other 11 patients the detachable coil embolization system was used. Twelve (55%) patients had no significant residual leaks immediately after the procedure involving a single coil delivery. The remaining 10 (45%) patients had residual leaks immediately after the procedure, although only 2 (9%) of the patients with a large ductus showed trace residual leakage 12 to 18 months after the procedure. During the radiographic measurement of coils, all implanted coils were shrunk to 65 to 85% of their original size immediately after occlusion. This shrinkage was more evident in patients exhibiting spontaneous closure of the residual shunt and/or having a coil 8 mm in diameter.Conclusions. Coil embolization is an acceptable method for occluding patent ductus arteriosus. Shrinkage of implanted coils is common in the follw-up period. Such shrinkage may be related to spontaneous closure of the residual shunt.

背景弹簧圈栓塞最近已被用作治疗动脉导管未闭的有效替代手术。本报告介绍了使用可脱性和不可脱性栓塞系统以及具有5个以上螺旋环的改良长Gianturco弹簧圈进行动脉导管未闭弹簧圈闭塞的结果。此外，它提供了一个中期的自然历史线圈植入导管。方法和结果。22例患者接受了弹簧圈闭塞术，年龄范围为2岁9个月至12岁10个月（平均（SY+-[）SD：6.5（SY+-[）3.6岁）。导管最大径1.0 ~ 3.5mm，平均2.6 ± 0.7mm。其中11例患者使用不可解脱系统植入常规弹簧圈，而其他11例患者使用可解脱弹簧圈栓塞系统。12例（55%）患者在涉及单弹簧圈输送的手术后立即没有明显的残余泄漏。其余10例（45%）患者在术后立即出现残余漏，但只有2例（9%）大导管患者在术后12 - 18个月出现微量残余漏。在弹簧圈的放射学测量过程中，所有植入的弹簧圈在闭塞后立即收缩至其原始尺寸的65%至85%。这种收缩在残余分流自发闭合和/或弹簧圈直径为8 mm的患者中更为明显。弹簧圈栓塞是一种可接受的动脉导管未闭封堵方法。植入弹簧圈的收缩在随访期间很常见。这种收缩可能与残余分流的自发闭合有关。

项目成果

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Kei Nishimoto：“动脉导管未闭弹簧圈栓塞的中期结果”日本微循环学会杂志 12. 615-616 (1995)。

井埜 利博: "動脈管開存症におけるコイル塞栓術-4" 日児誌. 99. 1133-1136 (1995)

Toshihiro Ino：“动脉导管未闭的线圈栓塞术-4”Nichiji Shi。99. 1133-1136 (1995)

Toshihiro Ino: "Recanalization after Coil Embolization of Patent Ducts Arteriosus" Heart. (in press). (1997)

Toshihiro Ino：“动脉导管未闭线圈栓塞后的再通”心脏。

Toshihiro Ino: "Catheter Occlusion of Patent Ductus Arteriosus Using Gianturco Coil -our experience-" J Am Coll Cardiol (in press). (1997)

Toshihiro Ino：“使用 Gianturco 线圈进行动脉导管闭塞 - 我们的经验 -”J Am Coll Cardiol（正在出版）。

Toshihiro Ino: "Catheter Occlusion of Patent Ductus Arteriosus Using Gianturco Coil-our experience-" J Am Coll Cardiol. (in press). (1997)

Toshihiro Ino：“使用 Gianturco 线圈进行动脉导管闭塞——我们的经验——”J Am Coll Cardiol。