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Study on the mechanism of idiopathic calcification in hard tissue of tooth

Study on the mechanism of idiopathic calcification in hard tissue of tooth
牙齿硬组织特发性钙化机制的研究
批准号:
07672004
负责人:
TANIGUCHI Kunihisa
金额:
$1.47万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1996

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中文摘要
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英文摘要
This study was designed to inbestigate the mechanism of the defects of hard tissue formtion by traumatic injury to tooth term, to examine on the relationship between the timing of trauma and the defects of hard tissue formation after trauma. We gave experimental traum by penetration to tooth germs at different developmental stages, and examined traumatic changes and the degree of disturbance. Taruma before matrix formation of enamel (postnatal 1 day) produced localized defects of amelogenesis and we obserbed the defect of enamel locally with a SEM image. Irregular dentin was fromed and normal dentin formation was grandually repaired. In trauma at the early stage of enamel matrix fomation (postnatal 3 days), the defects of amelopeneses and irregular dentine formation with the formed hard tissue before ftauma occurred. In SEM findings, morphological change occurred in the cuspid and enamel hypoplasia was observed partially. Trauma at satge of enamel matrix formation (postnatal 5,7 days) … More affected the plural cuspids and the defects of hard tissue formation occurred at the tooth cervix. The surface of enamel wasrough with SEM image. At the same time, the crown of tooth germ was displaced or ankylosis at the cervix with the disturbance of eruption was seen. It was speculated that the canses for the appearance of these tooth cervix were due to be subjected to load of strees by trauma at the stage of matrix formation. Odontblasts were partly detached from dentin. Irregular dentin with cellular inclusions were distributed and dentin formed after trauma showed thickeing. Trauma at the stage of calcification induced a slight injury of hard tissue, but showed the defects of hard tissue formation at the tooth cervix in many cases. It was seemed that trauma at the same stage induced hypocalcification because enamel matrix remained partly.It's suggested that the degree and location of defects of hard tissue formation were different degending on the timing of trauma to the tooth germ. Less
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The regeneration of tooth in combination with homologous transplantation of freezed tooth germ and non-freezed bone marrow tissue.
  • 批准号:
    15591960
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.86万
  • 财政年份:
    2003
  • 负责人:
    TANIGUCHI Kunihisa
  • 依托单位:
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亚低温调控颅脑创伤急性期神经干细胞Mpc2/Lactate/H3K9lac通路促进神经修复的研究
  • 批准号:
    82371379
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2023
  • 负责人:
    冯军峰
  • 依托单位:
儿童期受虐经历影响成年人群幸福感:行为、神经机制与干预研究
  • 批准号:
    32371121
  • 项目类别:
    面上项目
  • 资助金额:
    50.00万元
  • 批准年份:
    2023
  • 负责人:
    孔风
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精神创伤相关的抑郁症HPA轴功能与相关脑区磁共振特征研究
  • 批准号:
    81171286
  • 项目类别:
    面上项目
  • 资助金额:
    58.0万元
  • 批准年份:
    2011
  • 负责人:
    李凌江
  • 依托单位:
骨髓间充质干细胞转分化再生汗腺效能与功能评价研究
  • 批准号:
    30730090
  • 项目类别:
    重点项目
  • 资助金额:
    170.0万元
  • 批准年份:
    2007
  • 负责人:
    付小兵
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